Calculating all multiple parameter solutions of ODE models to avoid biological misinterpretations

DOI10.3934/MBE.2019322MaRDI QIDQ2045450zbMATH OpenOpenAlexWikidataFDO

Authors Maria Pia Saccomani, Karl Thomaseth

Publication date 13 August 2021

Published in Mathematical Biosciences and Engineering (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.3934/mbe.2019322

zbMATH Keywords

biological systemsdifferential equationHIV modellocal identifiabilitymultiple parameter solutionsparameter estimation

Mathematics Subject Classification ID

Nonlinear ordinary differential equations and systems (34A34) Qualitative investigation and simulation of ordinary differential equation models (34C60) Systems biology, networks (92C42)

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Cites work

• A fast algorithm to assess local structural identifiability
• An effective automatic procedure for testing parameter identifiability of HIV/AIDS models
• An investigation of the sources of nonuniqueness in deterministic identifiability
• Dynamics of HIV infection of CD4^ + T cells
• scientific article; zbMATH DE number 3997615 (Why is no real title available?)
• Minimal output sets for identifiability
• On global identifiability for arbitrary model parametrizations
• On the application of the Laplace transform to a particular case of ruin in ended times
• Parameter estimation of a model for baroreflex control of unstressed volume

Cited in

(5)

• The union between structural and practical identifiability makes strength in reducing oncological model complexity: a case study
• Computing all identifiable functions of parameters for ODE models
• Identifiability analysis of linear ordinary differential equation systems with a single trajectory
• A new version of DAISY to test structural identifiability of biological models
• Multi-experiment parameter identifiability of ODEs and model theory

Describes a project that uses

Uses Software

• PottersWheel
• DAISY
• PESTO
• GenSSI

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