Influence of nutrient availability and quorum sensing on the formation of metabolically inactive microcolonies within structurally heterogeneous bacterial biofilms: an individual-based 3D cellular automata model

DOI10.1007/S11538-017-0246-9MaRDI QIDQ2012318zbMATH OpenOpenAlexWikidataFDO

Authors Lakshmi Machineni, Anil Rajapantul, Vandana Nandamuri, Parag D. Pawar

Publication date 28 July 2017

Published in Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL http://raiith.iith.ac.in/3021/1/Manuscript%20I%2C%20BiofilmHeterogeneity%2C%20Lakshmi%20Machineni.pdf

zbMATH Keywords

heterogeneityquorum sensingbiofilmsautoinducerextracellular polymeric substancesmetabolic diversity

Mathematics Subject Classification ID

Physiological, cellular and medical topics (92C99) Cellular automata (computational aspects) (68Q80) Computational methods for problems pertaining to biology (92-08)

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Cites work

• A mathematical model of partial-thickness burn-wound infection by \textit{Pseudomonas aeruginosa}: quorum sensing and the build-up to invasion
• A multidimensional multispecies continuum model for heterogeneous biofilm development
• Finger formation in biofilm layers
• Lattice dynamics of II-VI mixed semiconductor \(\text{ZnS}_{1-x}\text{Se}_{x}\)
• Modelling antibiotic- and anti-quorum sensing treatment of a spatially-structured Pseudomonas aeruginosa population
• Traveling waves in response to a diffusing quorum sensing signal in spatially-extended bacterial colonies

Cited in

(5)

• Microcolony and biofilm formation as a survival strategy for bacteria
• Prediction and quantification of bacterial biofilm detachment using Glazier-Graner-Hogeweg method based model simulations
• Simulation-based exploration of quorum sensing triggered resistance of biofilms to antibiotics
• A pore-scale reactive transport modeling study for quorum sensing-driven biofilm dispersal in heterogeneous porous media
• Dynamic energy budget approach to evaluate antibiotic effects on biofilms

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Uses Software

• BacSim

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