L^1 penalization of volumetric dose objectives in optimal control of PDEs

DOI10.1007/S10589-017-9897-6MaRDI QIDQ2013147zbMATH OpenOpenAlexFDO

Authors Richard C. Barnard, Christian Clason

Publication date 3 August 2017

Published in Computational Optimization and Applications (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/1607.01655

zbMATH Keywords

optimal controlradiotherapysemi-smooth Newton method\(L^1\) penalizationdose volume constraints

Mathematics Subject Classification ID

Nonsmooth analysis (49J52) Existence theories for optimal control problems involving partial differential equations (49J20) Newton-type methods (49M15)

Abstract: This work is concerned with a class of optimal control problems governed by a partial differential equation that are motivated by an application in radiotherapy treatment planning, where the primary design objective is to minimize the volume where a functional of the state violates a prescribed level, but prescribing these levels in the form of pointwise state constraints can lead to infeasible problems. We therefore propose an alternative approach based on $L^1$ penalization of the violation. We establish well-posedness of the corresponding optimal control problem, derive first-order optimality conditions, and present a semismooth Newton method for the efficient numerical solution of these problems. The performance of this method for a model problem is illustrated and contrasted with the alternative approach based on (regularized) state constraints.

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