OPTIMAL RADIOTHERAPY TREATMENT PLANNING GOVERNED BY KINETIC EQUATIONS

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Publication:3560036

DOI10.1142/S0218202510004386zbMATH Open1255.49007arXiv0904.0740OpenAlexW2052378738MaRDI QIDQ3560036FDOQ3560036


Authors: Martin Frank, Michael Herty, Albert N. Sandjo Edit this on Wikidata


Publication date: 19 May 2010

Published in: M\(^3\)AS. Mathematical Models \& Methods in Applied Sciences (Search for Journal in Brave)

Abstract: In this paper we study a problem in radiotherapy treatment planning, where the evolution of the radiation field is governed by a deterministic Boltzmann transport equation. We show existence, uniqueness and regularity of solutions to an optimal dose distribution problem constrained by the Boltzmann Continuous Slowing-Down equation in an appropriate function space. The main new difficulty is the treatment of the stopping power term. Furthermore, we characterize optimal controls for problems governed by this transport equation.


Full work available at URL: https://arxiv.org/abs/0904.0740




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