ON THE FOUNDATIONS OF CANCER MODELLING: SELECTED TOPICS, SPECULATIONS, AND PERSPECTIVES

DOI10.1142/S0218202508002796zbMath1151.92014OpenAlexW2104010300MaRDI QIDQ3521624

Philip K. Maini, Natasha K. Li, Nicola Bellomo

Publication date: 26 August 2008

Published in: Mathematical Models and Methods in Applied Sciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1142/s0218202508002796

zbMATH Keywords

discrete models population dynamics kinetic theory continuum models multiscale modelling living systems mechanical models moving boundary models cellular tissue models complexity in biology macroscopic tissue models

Mathematics Subject Classification ID

Medical applications (general) (92C50)

Related Items

Etiology of phenotype switching strategy in time varying stochastic environment, Phase transitions in tumor growth. III: Vascular and metastasis behavior, A chaos study of tumor and effector cells in fractional tumor-immune model for cancer treatment, A mathematical model for the dynamics of cancer hepatocytes under therapeutic actions, Is the Allee effect relevant in cancer evolution and therapy?, Computational approaches and analysis for a spatio-structural-temporal invasive carcinoma model, Analysis of a tumor model as a multicomponent deformable porous medium, On the smoothness of the free boundary in a nonlocal one-dimensional parabolic free boundary value problem, Combination therapies and intra-tumoral competition: insights from mathematical modeling, A time delay model of tumour-immune system interactions: global dynamics, parameter estimation, sensitivity analysis, An optimal control approach for the treatment of solid tumors with angiogenesis inhibitors, Well-posedness for a class of phase-field systems modeling prostate cancer growth with fractional operators and general nonlinearities, Nonlinear optimization for a tumor invasion PDE model, An accurate front capturing scheme for tumor growth models with a free boundary limit, An adaptive rectangular mesh administration and refinement technique with application in cancer invasion models, Mechanistic model for cancer growth and response to chemotherapy, Interpreting stochastic agent-based models of cell death, Global existence for a haptotaxis model of cancer invasion with tissue remodeling, Modelling aggregation-fragmentation phenomena from kinetic to macroscopic scales, From kinetic models of multicellular growing systems to macroscopic biological tissue models, On the initial value problem of a class of models of the kinetic theory for active particles, Boundedness and asymptotic behavior of solutions to a chemotaxis-haptotaxis model in high dimensions, Ion transport in inhomogeneous media based on the bipartition model for primary ions, The nature of Hopf bifurcation for the Gompertz model with delays, Qualitative and computational analysis of a mathematical model for tumor-immune interactions, Asymptotic dynamics on a singular chemotaxis system modeling onset of tumor angiogenesis, Experimental versus numerical data for breast cancer progression, An inverse problem formulation for parameter estimation of a reaction-diffusion model of low grade gliomas, Global boundedness in a three-dimensional chemotaxis-haptotaxis model, Composite waves for a cell population system modeling tumor growth and invasion, On the modelling of genetic mutations and immune system competition, The role of dose density in combination cancer chemotherapy, Singular structure formation in a degenerate haptotaxis model involving myopic diffusion, Chaos in a tumor growth model with delayed responses of the immune system, The worst drug rule revisited: mathematical modeling of cyclic cancer treatments, Existence of solutions of cancer invasion parabolic system with integrable data, What does not kill a tumour may make it stronger: \textit{in silico} insights into chemotherapeutic drug resistance, A new conceptual framework for the therapy by optimized multidimensional pulses of therapeutic activity. The case of multiple myeloma model, A novel method for simulating the extracellular matrix in models of tumour growth, Hyperbolic and kinetic models for self-organized biological aggregations and movement: a brief review, Mathematical modeling of bone marrow -- peripheral blood dynamics in the disease state based on current emerging paradigms. II, Three-dimensional multispecies nonlinear tumor growth. II: Tumor invasion and angiogenesis, Tumour suppression by immune system through stochastic oscillations, Modeling anti-tumor Th1 and Th2 immunity in the rejection of melanoma, Mathematical and numerical analysis of an acid-mediated cancer invasion model with nonlinear diffusion, A partial differential equation model and its reduction to an ordinary differential equation model for prostate tumor growth under intermittent hormone therapy, Tumor growth in complex, evolving microenvironmental geometries: a diffuse domain approach, A validated mathematical model of tumor growth including tumor-host interaction, cell-mediated immune response and chemotherapy, Analysis of a Cahn-Hilliard-Brinkman model for tumour growth with chemotaxis, Adjoint method for a tumor invasion PDE-constrained optimization problem in 2D using adaptive finite element method, On a non-isothermal Cahn-Hilliard model for tumor growth, Modeling and simulation of vascular tumors embedded in evolving capillary networks, Boundedness of solutions to a quasilinear higher-dimensional chemotaxis-haptotaxis model with nonlinear diffusion, Global solutions for a hyperbolic-parabolic system of chemotaxis, Simulation of the phase field Cahn-Hilliard and tumor growth models via a numerical scheme: element-free Galerkin method, A phase-field approach to non-isothermal transitions, A mathematical method for parameter estimation in a tumor growth model, Toward predictive multiscale modeling of vascular tumor growth, computational and experimental oncology for tumor prediction, Existence and uniqueness of global classical solutions to a two dimensional two species cancer invasion haptotaxis model, On the probability of random genetic mutations for various types of tumor growth, On the derivation of macroscopic tissue equations from hybrid models of the kinetic theory of multicellular growing systems -- the effect of global equilibrium, An adaptive multigrid algorithm for simulating solid tumor growth using mixture models, A phenomenological approach to the dynamics of activation and clonal expansion of \(T\) cells, Comparison between two meshless methods based on collocation technique for the numerical solution of four-species tumor growth model, Evolution of a mathematical model of an aggressive-invasive cancer under chemotherapy, Angiogenesis inhibition and tumor-immune interactions with chemotherapy by a control set-valued method, A density-dependent chemotaxis-haptotaxis system modeling cancer invasion, Boundedness of solutions to a quasilinear chemotaxis-haptotaxis model, Macroscopic models for fibroproliferative disorders: a review, Individually-based Markov processes modeling nonlinear systems in mathematical biology, On the derivation of macroscopic hyperbolic equations for binary multicellular growing mixtures, The MWF method for kinetic equations system, Solutions of a linearized mathematical model for capillary formation in tumor angiogenesis: an initial data perturbation approximation, Optimal control of tumour-immune model with time-delay and immuno-chemotherapy, On a parabolic-elliptic chemotactic model with coupled boundary conditions, Nonlinear modeling with mammographic evidence of carcinoma, Modeling the hiding-learning dynamics in large living systems, Transport-diffusion models with nonlinear boundary conditions and solution by generalized collocation methods, The MWF method: A convergence theorem for homogeneous one-dimensional case, Convergence and positivity of finite element methods for a haptotaxis model of tumoral invasion, Optimal distributed control of a Cahn-Hilliard-Darcy system with mass sources, A general framework for modeling tumor-immune system competition at the mesoscopic level, On the modelling of space dynamics in the kinetic theory for active particles, Delay-induced oscillatory dynamics of tumour-immune system interaction, Nonlocal adhesion models for two cancer cell phenotypes in a multidimensional bounded domain, On the modeling of nonlinear interactions in large complex systems, On the fractional Fisher information with applications to a hyperbolic-parabolic system of chemotaxis, Solvability of solid tumor invasion model, From the mathematical kinetic theory for active particles on the derivation of hyperbolic macroscopic tissue models, Mathematical model and its fast numerical method for the tumor growth, On the coupling of higher and lower scales using the mathematical kinetic theory of active particles, Cahn-Hilliard-Brinkman systems for tumour growth, Growth of tumours with stem cells: the effect of crowding and ageing of cells, Algorithmic asymptotic analysis: extending the arsenal of cancer immunology modeling, PDE-constrained optimization in medical image analysis, Finite-element approximation of a phase field model for tumour growth, Propagation of chaos in the nonlocal adhesion models for two cancer cell phenotypes, Global dynamics of the model of tumor-immune interaction, Numerical analysis for a Cahn-Hilliard system modelling tumour growth with chemotaxis and active transport, Mathematical modeling of bone marrow -- peripheral blood dynamics in the disease state based on current emerging paradigms. I, Tumor evolution models of phase-field type with nonlocal effects and angiogenesis, Proportional observer design based on \(\mathcal{D}\)-stability and Finsler's lemma for Takagi-Sugeno systems, Modeling and analysis of nonlinear tumor‐immune interaction under chemotherapy and radiotherapy, Some further progress for boundedness of solutions to a quasilinear higher-dimensional chemotaxis-haptotaxis model with nonlinear diffusion, Boundedness in a two-dimensional two-species cancer invasion haptotaxis model without cell proliferation, Optimal control of an Allen-Cahn model for tumor growth through supply of cytotoxic drugs, Stochastic dynamics of nonlinear tumor-immune system with chemotherapy, The Aronson-Bénilan estimate in Lebesgue spaces, Chaotic transitions in a tumor-Immune model under chemotherapy treatment, A mathematical model of prostate tumor growth under hormone therapy with mutation inhibitor, A rigorous sharp interface limit of a diffuse interface model related to tumor growth, A multiscale approach to the migration of cancer stem cells: mathematical modelling and simulations, Global weak solutions in a three-dimensional two-species cancer invasion haptotaxis model without cell proliferation, IDENTIFICATION OF TEMPERATURE-DEPENDENT PARAMETERS IN LASER-INTERSTITIAL THERMO THERAPY, ENTROPY STRUCTURE OF A CROSS-DIFFUSION TUMOR-GROWTH MODEL, Numerical simulation of a thermodynamically consistent four-species tumor growth model, Spatial invasion dynamics on random and unstructured meshes: implications for heterogeneous tumor populations, Avoiding healthy cells extinction in a cancer model, Generalized collocation method for two-dimensional reaction-diffusion problems with homogeneous Neumann boundary conditions, Finite volume and WENO scheme in one-dimensional vascular system modelling, On the kinetic and stochastic games theory for active particles: Some reasonings on open large living systems, A with-in host dengue infection model with immune response, A bi-parametric model for the tumour angiogenesis and antiangiogenesis therapy, Multiscale cancer modeling: In the line of fast simulation and chemotherapy, Fast Parameter Estimation for Cancer Cell Progression and Response to Therapy, A model for acid-mediated tumour growth with nonlinear acid production term, The effect of time ordering and concurrency in a mathematical model of chemoradiotherapy, A hybrid ten-species phase-field model of tumor growth, Traveling wave solution of the Hele–Shaw model of tumor growth with nutrient, Boundedness and large time behavior in a quasilinear chemotaxis model for tumor invasion, Dynamics of a Mathematical Model of Cancer and Immunoediting Scenarios Under the Variation of the Immune Cell Activation Rate, Control of tumor growth distributions through kinetic methods, A model for transfer of P-glycoproteins in MCF-7 breast cancer cell line with multiple transfer rules, Stiff-response-induced instability for chemotactic bacteria and flux-limited Keller–Segel equation, A phenotype-structured model to reproduce the avascular growth of a tumor and its interaction with the surrounding environment, An optimal control problem of immuno-chemotherapy in presence of gene therapy, Melanoblast proliferation dynamics during mouse embryonic development. Modeling and validation, Bayesian inference using Gaussian process surrogates in cancer modeling, Reprint of: Bayesian inference using Gaussian process surrogates in cancer modeling, Large time behavior of solutions to a fully parabolic chemotaxis-haptotaxis model in \(N\) dimensions, A Mathematical Model of Cytokine Dynamics During a Cytokine Storm, Fokker–Planck equations in the modeling of socio-economic phenomena, Mathematical modelling of cancer invasion: The multiple roles of TGF-β pathway on tumour proliferation and cell adhesion, Interactions between the immune system and cancer: A brief review of non-spatial mathematical models, Stability analysis on a hybrid PDE–ODE system describing intermittent hormonal therapy of prostate cancer, The mathematical modeling of cancer growth and angiogenesis by an individual based interacting system, On a population dynamic model of active cells with direct interaction, Qualitative analysis and simulation of a nonlinear integro-differential system modeling tumor-immune cells competition, Mathematical analysis and simulation study of a phase-field model of prostate cancer growth with chemotherapy and antiangiogenic therapy effects, A kinetic theory approach for modelling tumour and macrophages heterogeneity and plasticity during cancer progression, Non-Maxwellian kinetic equations modeling the dynamics of wealth distribution, A mathematical model for progression and heterogeneity in colorectal cancer dynamics, A dynamical model of tumour immunotherapy, The Hele-Shaw asymptotics for mechanical models of tumor growth, Optimal Control Problem for Cancer Invasion Reaction–Diffusion System, Models of Cell Motion and Tissue Growth, Analysis of tumour-immune evasion with chemo-immuno therapeutic treatment with quadratic optimal control, A mathematical model of immune competition related to cancer dynamics, MATHEMATICAL MODELLING OF CANCER INVASION: THE IMPORTANCE OF CELL–CELL ADHESION AND CELL–MATRIX ADHESION, AN IN VITRO CELL POPULATION DYNAMICS MODEL INCORPORATING CELL SIZE, QUIESCENCE, AND CONTACT INHIBITION, Asymptotic analysis of a tumor growth model with fractional operators, ON OPTIMAL TREATMENT PLANNING IN RADIOTHERAPY GOVERNED BY TRANSPORT EQUATIONS, MATHEMATICAL MODELING FOR KELOID FORMATION TRIGGERED BY VIRUS: MALIGNANT EFFECTS AND IMMUNE SYSTEM COMPETITION, A mathematical model for progression and heterogeneity in colorectal cancer dynamics, GENERAL DIFFUSE-INTERFACE THEORIES AND AN APPROACH TO PREDICTIVE TUMOR GROWTH MODELING, OPTIMAL RADIOTHERAPY TREATMENT PLANNING GOVERNED BY KINETIC EQUATIONS, Optimal control problem for cancer invasion parabolic system with nonlinear diffusion, GLOBAL EXISTENCE AND ASYMPTOTIC BEHAVIOR OF A TUMOR ANGIOGENESIS MODEL WITH CHEMOTAXIS AND HAPTOTAXIS, Optimal control of cytotoxic and antiangiogenic therapies on prostate cancer growth, A NUMERICAL ANALYSIS OF A REACTION–DIFFUSION SYSTEM MODELING THE DYNAMICS OF GROWTH TUMORS, FROM THE MODELING OF THE IMMUNE HALLMARKS OF CANCER TO A BLACK SWAN IN BIOLOGY, ABOUT THE GENE FAMILIES SIZE DISTRIBUTION IN A RECENT MODEL OF GENOME EVOLUTION, SIZE DISTRIBUTION OF GENE FAMILIES IN A GENOME, Identification of crucial parameters in a mathematical multiscale model of glioblastoma growth, Delay differential model for tumour-immune response with chemoimmunotherapy and optimal control, Radially symmetric growth of nonnecrotic tumors, Slow and fast invasion waves in a model of acid-mediated tumour growth, ASYMPTOTIC BEHAVIOR OF GLOBAL SOLUTIONS TO A MODEL OF CELL INVASION, Certified reduced-order methods for optimal treatment planning, Optimal control of the dynamics of a tumor growth model with Hollings' type-II functional response, A mathematical model for the effect of obesity on cancer growth and on the immune system response, A Cahn–Hilliard–Darcy model for tumour growth with chemotaxis and active transport, CONTINUUM THERMODYNAMICS AND NONLINEAR PARTIAL DIFFERENTIAL EQUATIONS, Tumor Stabilization Induced by T-Cell Recruitment Fluctuations, Local and nonlocal phase-field models of tumor growth and invasion due to ECM degradation, On the unsteady Darcy–Forchheimer–Brinkman equation in local and nonlocal tumor growth models, MODELLING EPIDEMICS AND VIRUS MUTATIONS BY METHODS OF THE MATHEMATICAL KINETIC THEORY FOR ACTIVE PARTICLES, ON A MODEL FOR THE PROPAGATION OF ISOTOPIC DISEQUILIBRIUM BY DIFFUSION, A fully coupled space-time multiscale modeling framework for predicting tumor growth, Selection and validation of predictive models of radiation effects on tumor growth based on noninvasive imaging data, Simulation of glioblastoma growth using a 3D multispecies tumor model with mass effect, A MODEL AT THE MACROSCOPIC SCALE OF PROSTATE TUMOR GROWTH UNDER INTERMITTENT ANDROGEN SUPPRESSION, PATTERN FORMATION IN A RING NETWORK WITH DELAY, Selection, calibration, and validation of models of tumor growth, SELECTION AND ASSESSMENT OF PHENOMENOLOGICAL MODELS OF TUMOR GROWTH, A MULTIPHASE MODEL OF TUMOR AND TISSUE GROWTH INCLUDING CELL ADHESION AND PLASTIC REORGANIZATION, On a class of non-local phase-field models for tumor growth with possibly singular potentials, chemotaxis, and active transport, A solvable hyperbolic free boundary problem modelling tumour regrowth, Toward Understanding the Boundary Propagation Speeds in Tumor Growth Models, Effects of mutations and immunogenicity on outcomes of anti-cancer therapies for secondary lesions, Two positivity preserving flux limited, second-order numerical methods for a haptotaxis model, Efficiency of cancer treatments: in silico experiments, \textit{In silico} implementation of evolutionary paradigm in therapy design: towards anti-cancer therapy as Darwinian process, The effect of finite duration inputs on the dynamics of a system: Proposing a new approach for cancer treatment, Optimal control of stochastic phase-field models related to tumor growth, Mathematical modeling of the intracellular protein dynamics: the importance of active transport along microtubules, TOPOLOGICAL COMPLEXITY AND PREDICTABILITY IN THE DYNAMICS OF A TUMOR GROWTH MODEL WITH SHILNIKOV'S CHAOS, ON THE DIFFICULT INTERPLAY BETWEEN LIFE, "COMPLEXITY", AND MATHEMATICAL SCIENCES, MODELING THE EVOLUTION OF A TUMORAL MULTICELLULAR SPHEROID AS A TWO-FLUID BINGHAM-LIKE SYSTEM, Mean field dynamics of interaction processes with duplication, loss and copy

Uses Software

Chemotaxis

Cites Work