Existence and uniqueness of global classical solutions to a two dimensional two species cancer invasion haptotaxis model

DOI10.3934/DCDSB.2018169zbMATH Open1406.35429arXiv1704.08208OpenAlexW2608410300WikidataQ129154484 ScholiaQ129154484MaRDI QIDQ1756887FDOQ1756887

Authors: Jan Giesselmann, Niklas Kolbe, Nikolaos Sfakianakis, M. Lukáčová-Medvid'ová 

Publication date: 27 December 2018

Published in: Discrete and Continuous Dynamical Systems. Series B (Search for Journal in Brave)

Abstract: We consider a haptotaxis cancer invasion model that includes two families of cancer cells. Both families, migrate on the extracellular matrix and proliferate. Moreover the model describes an epithelial-to-mesenchymal-like transition between the two families, as well as a degradation and a self-reconstruction process of the extracellular matrix. We prove positivity and conditional global existence and uniqueness of the classical solutions of the problem for large initial data.

Full work available at URL: https://arxiv.org/abs/1704.08208

Recommendations

• Global boundedness of classical solutions to a two species cancer invasion haptotaxis model with tissue remodeling
• A new result for global solvability of a two species cancer invasion haptotaxis model with tissue remodeling
• Global solution for a chemotactic–haptotactic model of cancer invasion
• Global weak solutions in a three-dimensional two-species cancer invasion haptotaxis model without cell proliferation
• Global existence for a degenerate haptotaxis model of cancer invasion

zbMATH Keywords

cancer stem cellsclassical solutionshaptotaxis modeladvection-reaction-diffusioninvasion of the extracellular matrix

Mathematics Subject Classification ID

A priori estimates in context of PDEs (35B45) Smoothness and regularity of solutions to PDEs (35B65) Existence problems for PDEs: global existence, local existence, non-existence (35A01) Uniqueness problems for PDEs: global uniqueness, local uniqueness, non-uniqueness (35A02) Positive solutions to PDEs (35B09) PDEs in connection with biology, chemistry and other natural sciences (35Q92) General biology and biomathematics (92B05) Cell movement (chemotaxis, etc.) (92C17) Cell biology (92C37) Classical solutions to PDEs (35A09)

Cites Work

• Global existence of classical solutions to a combined chemotaxis-haptotaxis model with logistic source
• Geometric theory of semilinear parabolic equations
• On the global existence of solutions to an aggregation model
• Boundedness vs. blow-up in a chemotaxis system
• Global weak solutions in a PDE-ODE system modeling multiscale cancer cell invasion
• Random walk with persistence and external bias
• Two-dimensional Keller-Segel model: Optimal critical mass and qualitative properties of the solutions
• MATHEMATICAL MODELLING OF CANCER INVASION OF TISSUE: THE ROLE AND EFFECT OF NONLOCAL INTERACTIONS
• Convergence of a cancer invasion model to a logistic chemotaxis model
• MATHEMATICAL MODELLING OF CANCER CELL INVASION OF TISSUE: THE ROLE OF THE UROKINASE PLASMINOGEN ACTIVATION SYSTEM
• Mathematical modeling of cancer cell invasion of tissue: biological insight from mathematical analysis and computational simulation
• The two-dimensional Keller-Segel model after blow-up
• Initiation of slime mold aggregation viewed as an instability
• Towards the ultimate conservative difference scheme. IV: A new approach to numerical convection
• On the proportion of cancer stem cells in a tumour
• Strategies for cancer stem cell elimination: insights from mathematical modeling
• Additive Runge-Kutta schemes for convection-diffusion-reaction equations
• Mathematical Models of Avascular Tumor Growth
• ON THE FOUNDATIONS OF CANCER MODELLING: SELECTED TOPICS, SPECULATIONS, AND PERSPECTIVES
• Bi-CGSTAB: A Fast and Smoothly Converging Variant of Bi-CG for the Solution of Nonsymmetric Linear Systems
• Mathematical Modelling of Tumour Invasion and Metastasis
• Cancer Modelling and Simulation
• Implicit-explicit Runge-Kutta schemes and applications to hyperbolic systems with relaxation
• The Hele-Shaw asymptotics for mechanical models of tumor growth
• Energy-type estimates and global solvability in a two-dimensional chemotaxis-haptotaxis model with remodeling of non-diffusible attractant
• A mathematical insight in the epithelial-mesenchymal-like transition in cancer cells and its effect in the invasion of the extracellular matrix
• Global solutions of some chemotaxis and angiogenesis system in high space dimension
• Global existence for a haptotaxis model of cancer invasion with tissue remodeling
• BOUNDEDNESS OF SOLUTIONS OF A HAPTOTAXIS MODEL
• The Derivation of Chemotaxis Equations as Limit Dynamics of Moderately Interacting Stochastic Many-Particle Systems
• An application of the invariance principle to reaction diffusion equations
• Global Existence of Classical Solutions for a Haptotaxis Model
• A study on time discretization and adaptive mesh refinement methods for the simulation of cancer invasion: the urokinase model
• A multiscale approach to the migration of cancer stem cells: mathematical modelling and simulations
• Global existence for a go-or-grow multiscale model for tumor invasion with therapy

Cited In (14)

• A new result for global solvability of a two species cancer invasion haptotaxis model with tissue remodeling
• Global boundedness of classical solutions to a two species cancer invasion haptotaxis model with tissue remodeling
• Global boundedness for a \(N\)-dimensional two species cancer invasion haptotaxis model with tissue remodeling
• Global solvability and optimal control to a haptotaxis cancer invasion model with two cancer cell species
• Existence and uniqueness of local classical solutions to modified tumor invasion models of Chaplain-Anderson type
• Global Existence of Classical Solutions for a Haptotaxis Model
• Blow-up phenomena of a cancer invasion model with nonlinear diffusion and haptotaxis term
• Nonlocal adhesion models for two cancer cell phenotypes in a multidimensional bounded domain
• Global existence for a haptotaxis model of cancer invasion with tissue remodeling
• Boundedness in a flux-limited chemotaxis-haptotaxis model with nonlinear diffusion
• Global existence for a degenerate haptotaxis model of cancer invasion
• Global weak solutions in a three-dimensional two-species cancer invasion haptotaxis model without cell proliferation
• A hybrid multiscale model for cancer invasion of the extracellular matrix
• Boundedness in a two-dimensional two-species cancer invasion haptotaxis model without cell proliferation

This page was built for publication: Existence and uniqueness of global classical solutions to a two dimensional two species cancer invasion haptotaxis model

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q1756887)