Existence and uniqueness of global classical solutions to a two dimensional two species cancer invasion haptotaxis model
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cancer stem cellsclassical solutionshaptotaxis modeladvection-reaction-diffusioninvasion of the extracellular matrix
A priori estimates in context of PDEs (35B45) Smoothness and regularity of solutions to PDEs (35B65) Existence problems for PDEs: global existence, local existence, non-existence (35A01) Uniqueness problems for PDEs: global uniqueness, local uniqueness, non-uniqueness (35A02) Positive solutions to PDEs (35B09) PDEs in connection with biology, chemistry and other natural sciences (35Q92) General biology and biomathematics (92B05) Cell movement (chemotaxis, etc.) (92C17) Cell biology (92C37) Classical solutions to PDEs (35A09)
Abstract: We consider a haptotaxis cancer invasion model that includes two families of cancer cells. Both families, migrate on the extracellular matrix and proliferate. Moreover the model describes an epithelial-to-mesenchymal-like transition between the two families, as well as a degradation and a self-reconstruction process of the extracellular matrix. We prove positivity and conditional global existence and uniqueness of the classical solutions of the problem for large initial data.
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Cited in
(14)- Boundedness in a two-dimensional two-species cancer invasion haptotaxis model without cell proliferation
- Global boundedness of classical solutions to a two species cancer invasion haptotaxis model with tissue remodeling
- A new result for global solvability of a two species cancer invasion haptotaxis model with tissue remodeling
- Global boundedness for a \(N\)-dimensional two species cancer invasion haptotaxis model with tissue remodeling
- Global solvability and optimal control to a haptotaxis cancer invasion model with two cancer cell species
- Global Existence of Classical Solutions for a Haptotaxis Model
- Existence and uniqueness of local classical solutions to modified tumor invasion models of Chaplain-Anderson type
- Global existence for a haptotaxis model of cancer invasion with tissue remodeling
- Blow-up phenomena of a cancer invasion model with nonlinear diffusion and haptotaxis term
- Nonlocal adhesion models for two cancer cell phenotypes in a multidimensional bounded domain
- Boundedness in a flux-limited chemotaxis-haptotaxis model with nonlinear diffusion
- Global existence for a degenerate haptotaxis model of cancer invasion
- Global weak solutions in a three-dimensional two-species cancer invasion haptotaxis model without cell proliferation
- A hybrid multiscale model for cancer invasion of the extracellular matrix
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