Local and nonlocal phase-field models of tumor growth and invasion due to ECM degradation
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Publication:4973281
DOI10.1142/S0218202519500519zbMATH Open1425.35075arXiv1906.07788WikidataQ111491152 ScholiaQ111491152MaRDI QIDQ4973281FDOQ4973281
Authors: Marvin Fritz, E. A. B. F. Lima, Vanja Nikolić, J. Tinsley Oden, B. Wohlmuth 
Publication date: 3 December 2019
Published in: M\(^3\)AS. Mathematical Models \& Methods in Applied Sciences (Search for Journal in Brave)
Abstract: We present and analyze new multi-species phase-field mathematical models of tumor growth and ECM invasion. The local and nonlocal mathematical models describe the evolution of volume fractions of tumor cells, viable cells (proliferative and hypoxic cells), necrotic cells, and the evolution of MDE and ECM, together with chemotaxis, haptotaxis, apoptosis, nutrient distribution, and cell-to-matrix adhesion. We provide a rigorous proof of the existence of solutions of the coupled system with gradient-based and adhesion-based haptotaxis effects. In addition, we discuss finite element discretizations of the model, and we present the results of numerical experiments designed to show the relative importance and roles of various effects, including cell mobility, proliferation, necrosis, hypoxia, and nutrient concentration on the generation of MDEs and the degradation of the ECM.
Full work available at URL: https://arxiv.org/abs/1906.07788
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Existence problems for PDEs: global existence, local existence, non-existence (35A01) Weak solutions to PDEs (35D30) Initial-boundary value problems for higher-order parabolic equations (35K35) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Finite element, Rayleigh-Ritz and Galerkin methods for initial value and initial-boundary value problems involving PDEs (65M60) Finite element methods applied to problems in fluid mechanics (76M10) Physiological flows (76Z05) Cell movement (chemotaxis, etc.) (92C17)
Cites Work
- Mathematical tools for the study of the incompressible Navier-Stokes equations and related models
- Compact sets in the space \(L^ p(0,T;B)\)
- A history of the study of solid tumour growth: the contribution of mathematical modelling
- On a Cahn-Hilliard type phase field system related to tumor growth
- Analysis.
- Infinite-dimensional dynamical systems. An introduction to dissipative parabolic PDEs and the theory of global attractors
- Global weak solutions in a PDE-ODE system modeling multiscale cancer cell invasion
- Numerical simulation of a thermodynamically consistent four-species tumor growth model
- A chemotaxis-haptotaxis model: the roles of nonlinear diffusion and logistic source
- Weakly Differentiable Functions
- A nonlocal vector calculus, nonlocal volume-constrained problems, and nonlocal balance laws
- Convergence of a cancer invasion model to a logistic chemotaxis model
- Title not available (Why is that?)
- A diffuse interface model for two-phase incompressible flows with non-local interactions and non-constant mobility
- Title not available (Why is that?)
- MATHEMATICAL MODELLING OF CANCER CELL INVASION OF TISSUE: THE ROLE OF THE UROKINASE PLASMINOGEN ACTIVATION SYSTEM
- ON THE FOUNDATIONS OF CANCER MODELLING: SELECTED TOPICS, SPECULATIONS, AND PERSPECTIVES
- Mathematical Modelling of Tumour Invasion and Metastasis
- Title not available (Why is that?)
- Applied functional analysis. Functional analysis, Sobolev spaces and elliptic differential equations
- On continuity of functions with values in various Banach spaces
- Localization of nonlocal gradients in various topologies
- Mathematical modelling of cancer cell invasion of tissue: local and non-local models and the effect of adhesion
- Mathematical modelling of cancer invasion: the importance of cell -- cell adhesion and cell -- matrix adhesion
- Traveling Shock Waves Arising in a Model of Malignant Invasion
- Nonlinear partial differential equations with applications
- Three-dimensional multispecies nonlinear tumor growth. I: Model and numerical method
- A continuum approach to modelling cell-cell adhesion
- Travelling wave solutions to a haptotaxis-dominated model of malignant invasion
- Multiscale cancer modeling. Selected contributions based on the presentations at the 1st Transatlantic workshop on multiscale cancer modeling, Brussels, Belgium, October 23--24, 2008
- A multiscale mathematical model of tumour invasive growth
- Global Existence of Classical Solutions for a Haptotaxis Model
- On the approximation and efficient evaluation of integral terms in PDE models of cell adhesion
- Analysis of a diffuse interface model of multispecies tumor growth
- On a Cahn-Hilliard-Darcy system for tumour growth with solution dependent source terms
- Global weak solutions and asymptotic limits of a Cahn-Hilliard-Darcy system modelling tumour growth
- Well-posedness and long-time behavior of a non-autonomous Cahn-Hilliard-Darcy system with mass source modeling tumor growth
- A Cahn-Hilliard-Darcy model for tumour growth with chemotaxis and active transport
- A hybrid ten-species phase-field model of tumor growth
- Well-posedness of a Cahn-Hilliard system modelling tumour growth with chemotaxis and active transport
- Analysis and numerical solution of stochastic phase‐field models of tumor growth
- Toward predictive multiscale modeling of vascular tumor growth, computational and experimental oncology for tumor prediction
- Necessary and sufficient conditions for the chain rule in \(W_{\text{loc}}^{1,1} (\mathbb R^N;\mathbb R^d)\) and \(BV_{\text{loc}}(\mathbb R^N;\mathbb R^d)\)
- On a diffuse interface model for tumour growth with non-local interactions and degenerate mobilities
- Erratum to: ``On the nonlocal Cahn-Hilliard-Brinkman and Cahn-Hilliard-Hele-Shaw systems
- Selection and validation of predictive models of radiation effects on tumor growth based on noninvasive imaging data
- Thermodynamically consistent Navier–Stokes–Cahn–Hilliard models with mass transfer and chemotaxis
- A multiphase Cahn-Hilliard-Darcy model for tumour growth with necrosis
- A chain rule formula for the composition of a vector-valued function by a piecewise smooth function
- Title not available (Why is that?)
- On a structured multiscale model for acid-mediated tumor invasion: the effects of adhesion and proliferation
- Analysis of a Cahn-Hilliard-Brinkman model for tumour growth with chemotaxis
- On a Cahn-Hilliard-Brinkman model for tumor growth and its singular limits
- The nonlocal Cahn–Hilliard–Hele–Shaw system with logarithmic potential
- On the unsteady Darcy-Forchheimer-Brinkman equation in local and nonlocal tumor growth models
Cited In (21)
- Strong well-posedness and inverse identification problem of a non-local phase field tumour model with degenerate mobilities
- Tumor evolution models of phase-field type with nonlocal effects and angiogenesis
- Optimal distributed control for a viscous non-local tumour growth model
- Stability and error estimates of Strang splitting method for the nonlocal ternary conservative Allen-Cahn model
- An asymptotic analysis and numerical simulation of a prostate tumor growth model via the generalized moving least squares approximation combined with semi-implicit time integration
- Linearly implicit schemes preserve the maximum bound principle and energy dissipation for the time-fractional Allen-Cahn equation
- Complex far-field geometries determine the stability of solid tumor growth with chemotaxis
- Parameter identification for nonlocal phase field models for tumor growth via optimal control and asymptotic analysis
- Modeling and simulation of vascular tumors embedded in evolving capillary networks
- Maximal regularity and optimal control for a non-local Cahn-Hilliard tumour growth model
- Time-fractional Cahn-Hilliard equation: well-posedness, degeneracy, and numerical solutions
- On a class of non-local phase-field models for tumor growth with possibly singular potentials, chemotaxis, and active transport
- On the unsteady Darcy-Forchheimer-Brinkman equation in local and nonlocal tumor growth models
- Analysis of a new multispecies tumor growth model coupling 3D phase-fields with a 1D vascular network
- Multiphase modeling of tumor growth with matrix remodeling and fibrosis
- On the well-posedness of the Cahn-Hilliard-Biot model and its applications to tumor growth
- Nonlocal Cahn-Hilliard-Hele-Shaw systems with singular potential and degenerate mobility
- Stability and error analysis of structure-preserving schemes for a diffuse-interface tumor growth model
- The influence of soluble fragments of extracellular matrix (ECM) on tumor growth and morphology
- Global weak solutions in a three-dimensional two-species cancer invasion haptotaxis model without cell proliferation
- Nonlinear simulation of vascular tumor growth with chemotaxis and the control of necrosis
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