Analysis of a diffuse interface model of multispecies tumor growth
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Publication:5346535
DOI10.1088/1361-6544/AA6063zbMATH Open1367.35185arXiv1507.07683OpenAlexW2963683463WikidataQ59316409 ScholiaQ59316409MaRDI QIDQ5346535FDOQ5346535
Authors: Mimi Dai, Eduard Feireisl, Elisabetta Rocca, Giulio Schimperna, Maria E. Schonbek 
Publication date: 24 May 2017
Published in: Nonlinearity (Search for Journal in Brave)
Abstract: We consider a diffuse interface model for tumor growth recently proposed in [Y. Chen, S.M. Wise, V.B. Shenoy, J.S. Lowengrub, A stable scheme for a nonlinear, multiphase tumor growth model with an elastic membrane, Int. J. Numer. Methods Biomed. Eng., 30 (2014), 726-754]. In this new approach sharp interfaces are replaced by narrow transition layers arising due to adhesive forces among the cell species. Hence, a continuum thermodynamically consistent model is introduced. The resulting PDE system couples four different types of equations: a Cahn-Hilliard type equation for the tumor cells (which include proliferating and dead cells), a Darcy law for the tissue velocity field, whose divergence may be different from 0 and depend on the other variables, a transport equation for the proliferating (viable) tumor cells, and a quasi-static reaction diffusion equation for the nutrient concentration. We establish existence of weak solutions for the PDE system coupled with suitable initial and boundary conditions. In particular, the proliferation function at the boundary is supposed to be nonnegative on the set where the velocity satisfies , where is the outer normal to the boundary of the domain. We also study a singular limit as the diffuse interface coefficient tends to zero.
Full work available at URL: https://arxiv.org/abs/1507.07683
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Cahn-Hilliard equationreaction-diffusion equationtumor growthweak solutiondiffuse interface modelsingular limitsDarcy law
PDEs in connection with fluid mechanics (35Q35) Biological applications of optics and electromagnetic theory (78A70) Singular perturbations in context of PDEs (35B25) Weak solutions to PDEs (35D30) Initial-boundary value problems for higher-order parabolic equations (35K35) Reaction-diffusion equations (35K57) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Flows in porous media; filtration; seepage (76S05) Cell movement (chemotaxis, etc.) (92C17) Cell biology (92C37)
Cites Work
- Nonlinear simulations of solid tumor growth using a mixture model: invasion and branching
- A history of the study of solid tumour growth: the contribution of mathematical modelling
- On a Cahn-Hilliard type phase field system related to tumor growth
- Numerical simulation of a thermodynamically consistent four-species tumor growth model
- General diffuse-interface theories and an approach to predictive tumor growth modeling
- Nonlinear modelling of cancer: bridging the gap between cells and tumours
- Finite element approximation of the Navier-Stokes equations
- Bayesian calibration, validation, and uncertainty quantification of diffuse interface models of tumor growth
- MATHEMATICAL ANALYSIS AND CHALLENGES ARISING FROM MODELS OF TUMOR GROWTH
- Analysis of a mixture model of tumor growth
- Three-dimensional multispecies nonlinear tumor growth. I: Model and numerical method
- Selection and assessment of phenomenological models of tumor growth
- On a diffuse interface model of tumour growth
- Mathematical modelling of tumour growth and treatment
- An adaptive multigrid algorithm for simulating solid tumor growth using mixture models
- Asymptotic analyses and error estimates for a Cahn-Hilliard type phase field system modelling tumor growth
- Vanishing viscosities and error estimate for a Cahn-Hilliard type phase field system related to tumor growth
- Well-posedness and long-time behavior of a non-autonomous Cahn-Hilliard-Darcy system with mass source modeling tumor growth
- A Cahn-Hilliard-Darcy model for tumour growth with chemotaxis and active transport
- Well-posedness of a Cahn-Hilliard system modelling tumour growth with chemotaxis and active transport
- On the Cahn-Hilliard-Brinkman system
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- Optimal distributed control for a Cahn-Hilliard type phase field system related to tumor growth
- Second-Order Sufficient Conditions in the Sparse Optimal Control of a Phase Field Tumor Growth Model with Logarithmic Potential
- Does Maxwell's hypothesis of air saturation near the surface of evaporating liquid hold at all spatial scales?
- Optimal control of a phase field tumor growth model with chemotaxis and active transport
- Convergence rate for the incompressible limit of nonlinear diffusion-advection equations
- A rigorous approach to the sharp interface limit for phase-field models of tumor growth
- A fully-decoupled discontinuous Galerkin approximation of the Cahn–Hilliard–Brinkman–Ohta–Kawasaki tumor growth model
- Strong well-posedness and inverse identification problem of a non-local phase field tumour model with degenerate mobilities
- On a nonlinear model for tumor growth in a cellular medium
- Tumor evolution models of phase-field type with nonlocal effects and angiogenesis
- On a Cahn-Hilliard-Keller-Segel model with generalized logistic source describing tumor growth
- Numerical analysis for a Cahn-Hilliard system modelling tumour growth with chemotaxis and active transport
- Interface dynamics in a two-phase tumor growth model
- On a multi-species Cahn-Hilliard-Darcy tumor growth model with singular potentials
- Numerical analysis for the Cahn-Hilliard-Hele-Shaw system with variable mobility and logarithmic Flory-Huggins potential
- On a non-isothermal Cahn-Hilliard model for tumor growth
- Long-time dynamics and optimal control of a diffuse interface model for tumor growth
- Asymptotic analysis of a tumor growth model with fractional operators
- Optimal control of a phase field system modelling tumor growth with chemotaxis and singular potentials
- An analytic solution for a Gompertz-like reaction-diffusion model for tumour growth
- The Cahn-Hilliard-Hele-Shaw system with singular potential
- On a Cahn-Hilliard-Brinkman model for tumor growth and its singular limits
- Optimality conditions for an extended tumor growth model with double obstacle potential via deep quench approach
- Optimal distributed control of a Cahn-Hilliard-Darcy system with mass sources
- On the nonlocal Cahn-Hilliard-Brinkman and Cahn-Hilliard-Hele-Shaw systems
- Local and nonlocal phase-field models of tumor growth and invasion due to ECM degradation
- Long time dynamics of a phase-field model of prostate cancer growth with chemotherapy and antiangiogenic therapy effects
- Interactions between a uniformly proliferating tumour and its surroundings: uniform material properties
- The Cahn-Hilliard equation and some of its variants
- Second-order analysis of an optimal control problem in a phase field tumor growth model with singular potentials and chemotaxis
- Existence of weak solutions to a cross-diffusion Cahn-Hilliard type system
- Optimal treatment for a phase field system of Cahn-Hilliard type modeling tumor growth by asymptotic scheme
- Optimal distributed control of an extended model of tumor growth with logarithmic potential
- Varifold solutions of a sharp interface limit of a diffuse interface model for tumor growth
- Penalisation of long treatment time and optimal control of a tumour growth model of Cahn-Hilliard type with singular potential
- On the long time behavior of a tumor growth model
- Well-posedness of a diffuse interface model for Hele-Shaw flows
- Global weak solutions and asymptotic limits of a Cahn-Hilliard-Darcy system modelling tumour growth
- Parameter identification for nonlocal phase field models for tumor growth via optimal control and asymptotic analysis
- Sliding mode control for a phase field system related to tumor growth
- Optimal control of an Allen-Cahn model for tumor growth through supply of cytotoxic drugs
- On a diffuse interface model of tumour growth
- Global weak solutions to a Navier-Stokes-Cahn-Hilliard system with chemotaxis and singular potential
- Well-posedness for a class of phase-field systems modeling prostate cancer growth with fractional operators and general nonlinearities
- Global well-posedness of a Navier-Stokes-Cahn-Hilliard system with chemotaxis and singular potential in 2D
- Sharp interface limit of a diffuse interface model for tumor-growth
- A rigorous sharp interface limit of a diffuse interface model related to tumor growth
- Analysis of a tumor model as a multicomponent deformable porous medium
- On a class of non-local phase-field models for tumor growth with possibly singular potentials, chemotaxis, and active transport
- On the Existence of Strong Solutions to the Cahn--Hilliard--Darcy System with Mass Source
- Optimal control problems with sparsity for tumor growth models involving variational inequalities
- Numerical simulation of a thermodynamically consistent four-species tumor growth model
- Existence of weak solutions to multiphase Cahn-Hilliard-Darcy and Cahn-Hilliard-Brinkman models for stratified tumor growth with chemotaxis and general source terms
- Tumor growth in complex, evolving microenvironmental geometries: a diffuse domain approach
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- A coupled mass transport and deformation theory of multi-constituent tumor growth
- Nonlocal Cahn-Hilliard-Hele-Shaw systems with singular potential and degenerate mobility
- Optimal distributed control of two-dimensional Navier-Stokes-Cahn-Hilliard system with chemotaxis and singular potential
- Optimal control of treatment time in a diffuse interface model of tumor growth
- Analysis and numerical solution of stochastic phase‐field models of tumor growth
- The multicomponent diffuse-interface model and its application to water/air interfaces
- The nonlocal Cahn–Hilliard–Hele–Shaw system with logarithmic potential
- A multiphase Cahn-Hilliard-Darcy model for tumour growth with necrosis
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