An optimal control approach for the treatment of solid tumors with angiogenesis inhibitors

DOI10.3390/MATH5040049MaRDI QIDQ1649031zbMATH OpenOpenAlexFDO

Authors Adam E. Glick, Antonio Mastroberardino

Publication date 5 July 2018

Published in Mathematics (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.3390/math5040049

zbMATH Keywords

optimal control theoryanti-angiogenesis therapyoptimal dosing scheme

Mathematics Subject Classification ID

Medical applications (general) (92C50) Optimality conditions for problems involving ordinary differential equations (49K15) Applications of optimal control and differential games (49N90)

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Cites work

• scientific article; zbMATH DE number 3167340 (Why is no real title available?)
• scientific article; zbMATH DE number 3505708 (Why is no real title available?)
• A Multiple Scale Model for Tumor Growth
• A cellular automaton model for tumour growth in inhomogeneous environment
• AntiAngiogenic Therapy in Cancer Treatment as an Optimal Control Problem
• Mesoscopic and continuum modelling of angiogenesis
• ON THE FOUNDATIONS OF CANCER MODELLING: SELECTED TOPICS, SPECULATIONS, AND PERSPECTIVES
• Optimal control applied to biological models.
• Optimal scheduling of radiotherapy and angiogenic inhibitors
• Simple ODE models of tumor growth and anti-angiogenic or radiation treatment
• Tumour eradication by antiangiogenic therapy: analysis and extensions of the model by Hahnfeldt et al. (1999)

Cited in

(12)

• A topology Nash game for tumoral antiangiogenesis
• scientific article; zbMATH DE number 5556354 (Why is no real title available?)
• Optimal control of cytotoxic and antiangiogenic therapies on prostate cancer growth
• Angiogenesis inhibition and tumor-immune interactions with chemotherapy by a control set-valued method
• Dynamic behaviour and stabilisation to boost the immune system by complex interaction between tumour cells and vitamins intervention
• An optimization method for treating solid tumors with combined therapy using the great deluge algorithm
• Realizable protocols for optimal administration of drugs in mathematical models for anti-angiogenic treatment
• Dynamical systems analysis as an additional tool to inform treatment outcomes: the case study of a quantitative systems pharmacology model of immuno-oncology
• Optimal control of effector-tumor-normal cells dynamics in presence of adoptive immunotherapy
• STUDY ON THE DYNAMICS OF A PIECEWISE TUMOR–IMMUNE INTERACTION MODEL
• Combined therapy for treating solid tumors with chemotherapy and angiogenic inhibitors
• AntiAngiogenic Therapy in Cancer Treatment as an Optimal Control Problem

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