Mesoscopic and continuum modelling of angiogenesis
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Publication:2512944
Abstract: Angiogenesis is the formation of new blood vessels from pre-existing ones in response to chemical signals secreted by, for example, a wound or a tumour. In this paper, we propose a mesoscopic lattice-based model of angiogenesis, in which processes that include proliferation and cell movement are considered as stochastic events. By studying the dependence of the model on the lattice spacing and the number of cells involved, we are able to derive the deterministic continuum limit of our equations and compare it to similar existing models of angiogenesis. We further identify conditions under which the use of continuum models is justified, and others for which stochastic or discrete effects dominate. We also compare different stochastic models for the movement of endothelial tip cells which have the same macroscopic, deterministic behaviour, but lead to markedly different behaviour in terms of production of new vessel cells.
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Cites work
- scientific article; zbMATH DE number 484710 (Why is no real title available?)
- scientific article; zbMATH DE number 1014078 (Why is no real title available?)
- scientific article; zbMATH DE number 2148204 (Why is no real title available?)
- scientific article; zbMATH DE number 3806623 (Why is no real title available?)
- A Multiple Scale Model for Tumor Growth
- A cell-based model of endothelial cell migration, proliferation and maturation during corneal angiogenesis
- A history of the study of solid tumour growth: the contribution of mathematical modelling
- A hybrid continuum-discrete modelling approach to predict and control angiogenesis: analysis of combinatorial growth factor and matrix effects on vessel-sprouting morphology
- A mathematical model of vascular tumour growth and invasion
- A mathematical model to study the effects of drug resistance and vasculature on the response of solid tumors to chemotherapy
- A multiphase model describing vascular tumour growth
- A pharmacologically based multiscale mathematical model of angiogenesis and its use in investigating the efficacy of a new cancer treatment strategy
- A reinforced random walk model of tumour angiogenesis and anti-angiogenic strategies
- A user's guide to PDE models for chemotaxis
- Aggregation, Blowup, and Collapse: The ABC's of Taxis in Reinforced Random Walks
- Angiogenesis and vascular remodelling in normal and cancerous tissues
- Avascular growth, angiogenesis and vascular growth in solid tumours: The mathematical modelling of the stages of tumour development
- CELLULAR AUTOMATON MODELS OF TUMOR DEVELOPMENT: A CRITICAL REVIEW
- Continuous and discrete mathematical models of tumor-induced angiogenesis
- Lattice and non-lattice models of tumour angiogenesis
- Mathematical Models of Avascular Tumor Growth
- Mathematical modeling of capillary formation and development in tumor angiogenesis: penetration into the stroma
- Mathematical modeling of the onset of capillary formation initiating angiogenesis
- Mathematical modeling of tumor-induced angiogenesis
- Mathematical modelling of dynamic adaptive tumour-induced angiogenesis: clinical implications and therapeutic targeting strategies
- Mathematical modelling of flow through vascular networks: implications for tumour-induced angiogenesis and chemotherapy strategies
- Mathematical models for tumour angiogenesis: Numerical simulations and nonlinear wave solutions
- Mechanics and chemotaxis in the morphogenesis of vascular networks
- Multiscale modelling and nonlinear simulation of vascular tumour growth
- Partial differential equations of chemotaxis and angiogenesis
- Simple ODE models of tumor growth and anti-angiogenic or radiation treatment
- Stochastic modelling of tumour-induced angiogenesis
- Three-dimensional multispecies nonlinear tumor growth. II: Tumor invasion and angiogenesis
- Tumour eradication by antiangiogenic therapy: analysis and extensions of the model by Hahnfeldt et al. (1999)
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- A Multiscale Approach Leading to Hybrid Mathematical Models for Angiogenesis: The Role of Randomness
- Stochastic models of blood vessel growth
- A hybrid model to test the importance of mechanical cues driving cell migration in angiogenesis
- Angiogenesis: dynamics of endothelial cells in sprouting and bifurcation
- Gibbs point field model quantifies disorder in microvasculature of U87-glioblastoma
- A discrete mathematical model for angiogenesis
- A mathematical model of angiogenesis and tumor growth: analysis and application in anti-angiogenesis therapy
- Time changes in the VEGF-A concentration gradient lead neovasculature to engage in stair-like growth
- Variance-Reduced Simulation of Multiscale Tumor Growth Modeling
- Comparative analysis of continuum angiogenesis models
- Lattice and non-lattice models of tumour angiogenesis
- Wavefront of an angiogenesis model
- Stochastic modelling of viral blips in HIV-1-infected patients: effects of inhomogeneous density fluctuations
- Multi-scale analysis of angiogenic dynamics and therapy
- A coupled stochastic differential reaction-diffusion system for angiogenesis
- Multiscale modeling and simulation of traveling waves in biology: a review
- Simulating the behaviour of glioblastoma multiforme based on patient MRI during treatments
- Capturing the dynamics of a hybrid multiscale cancer model with a continuum model
- Mathematical modeling for angiogenesis
- An optimal control approach for the treatment of solid tumors with angiogenesis inhibitors
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