A mathematical model for the dynamics of cancer hepatocytes under therapeutic actions

DOI10.1016/J.JTBI.2011.11.022MaRDI QIDQ285210zbMATH OpenOpenAlexWikidataFDO

Authors Marcello Delitala, T. Lorenzi

Publication date 19 May 2016

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2011.11.022

zbMATH Keywords

evolutionstructured populationscancer modeling and therapyconcentration phenomenahepatocelular carcinoma

Mathematics Subject Classification ID

Medical applications (general) (92C50)

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Cites work

• scientific article; zbMATH DE number 3835792 (Why is no real title available?)
• A mathematical model for progression and heterogeneity in colorectal cancer dynamics
• Cancer immunotherapy, mathematical modeling and optimal control
• Evolution of resistance to anti-cancer therapy during general dosing schedules
• Individual cell-based models of cell scatter of ARO and MLP-29 cells in response to hepatocyte growth factor
• Investigating the link between epithelial-mesenchymal transition and the cancer stem cell phenotype: a mathematical approach
• Mathematical modeling of complex biological systems. A kinetic theory approach. With a preface by Nicola Bellomo.
• Mathematical modelling of the influence of heat shock proteins on cancer invasion of tissue
• ON THE FOUNDATIONS OF CANCER MODELLING: SELECTED TOPICS, SPECULATIONS, AND PERSPECTIVES
• On selection dynamics for continuous structured populations
• The dynamics of adaptation: An illuminating example and a Hamilton--Jacobi approach
• Transport equations in biology.

Cited in

(13)

• A mathematical model for immune and autoimmune response mediated by \(T\)-cells
• Evolutionary dynamics of competing phenotype-structured populations in periodically fluctuating environments
• Application of a two-phenotype color-shift model with heterogeneous growth to a rat hepatocarcinogenesis experiment
• A model for hepatocarcinogenesis treating phenotypical changes in focal hepatocellular lesions as epigenetic events
• Discrete and continuum models for the evolutionary and spatial dynamics of cancer: a very short introduction through two case studies
• Combination therapies and intra-tumoral competition: insights from mathematical modeling
• The role of spatial variations of abiotic factors in mediating intratumour phenotypic heterogeneity
• Evolution of cancer cell populations under cytotoxic therapy and treatment optimisation: insight from a phenotype-structured model
• Individual cell-based models of cell scatter of ARO and MLP-29 cells in response to hepatocyte growth factor
• Application of a color-shift model with heterogeneous growth to a rat hepatocarcinogenesis experiment
• Emergence of spatial patterns in a mathematical model for the co-culture dynamics of epithelial-like and mesenchymal-like cells
• Discrete and continuum phenotype-structured models for the evolution of cancer cell populations under chemotherapy
• Dissecting the dynamics of epigenetic changes in phenotype-structured populations exposed to fluctuating environments

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