A mathematical model for the dynamics of cancer hepatocytes under therapeutic actions

DOI10.1016/J.JTBI.2011.11.022zbMATH Open1336.92037OpenAlexW1996722469WikidataQ51483057 ScholiaQ51483057MaRDI QIDQ285210FDOQ285210

Authors: Marcello Delitala, T. Lorenzi 

Publication date: 19 May 2016

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2011.11.022

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zbMATH Keywords

evolutionstructured populationscancer modeling and therapyconcentration phenomenahepatocelular carcinoma

Mathematics Subject Classification ID

Medical applications (general) (92C50)

Cites Work

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• Individual cell-based models of cell scatter of ARO and MLP-29 cells in response to hepatocyte growth factor
• Cancer immunotherapy, mathematical modeling and optimal control
• Evolution of resistance to anti-cancer therapy during general dosing schedules
• Investigating the link between epithelial-mesenchymal transition and the cancer stem cell phenotype: a mathematical approach
• Mathematical modelling of the influence of heat shock proteins on cancer invasion of tissue
• The dynamics of adaptation: An illuminating example and a Hamilton--Jacobi approach
• Mathematical modeling of complex biological systems. A kinetic theory approach. With a preface by Nicola Bellomo.
• A mathematical model for progression and heterogeneity in colorectal cancer dynamics
• On selection dynamics for continuous structured populations

Cited In (13)

• A mathematical model for immune and autoimmune response mediated by \(T\)-cells
• Evolutionary dynamics of competing phenotype-structured populations in periodically fluctuating environments
• Application of a two-phenotype color-shift model with heterogeneous growth to a rat hepatocarcinogenesis experiment
• A model for hepatocarcinogenesis treating phenotypical changes in focal hepatocellular lesions as epigenetic events
• Discrete and continuum models for the evolutionary and spatial dynamics of cancer: a very short introduction through two case studies
• Evolution of cancer cell populations under cytotoxic therapy and treatment optimisation: insight from a phenotype-structured model
• Combination therapies and intra-tumoral competition: insights from mathematical modeling
• The role of spatial variations of abiotic factors in mediating intratumour phenotypic heterogeneity
• Individual cell-based models of cell scatter of ARO and MLP-29 cells in response to hepatocyte growth factor
• Application of a color-shift model with heterogeneous growth to a rat hepatocarcinogenesis experiment
• Emergence of spatial patterns in a mathematical model for the co-culture dynamics of epithelial-like and mesenchymal-like cells
• Discrete and continuum phenotype-structured models for the evolution of cancer cell populations under chemotherapy
• Dissecting the dynamics of epigenetic changes in phenotype-structured populations exposed to fluctuating environments

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