Role of regulatory T cells on a simple tumor-immune interaction system

DOI10.1016/J.CNSNS.2021.105765MaRDI QIDQ2025486zbMATH OpenOpenAlexFDO

Authors Peng Feng, Menaka Navaratna

Publication date 14 May 2021

Published in Communications in Nonlinear Science and Numerical Simulation (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.cnsns.2021.105765

zbMATH Keywords

immunotherapyordinary differential equationsregulatory T cells

Mathematics Subject Classification ID

Qualitative investigation and simulation of ordinary differential equation models (34C60) Medical applications (general) (92C50)

Recommendations

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Cites work

• An extended mathematical model of tumor growth and its interaction with the immune system, to be used for developing an optimized immunotherapy treatment protocol
• Mathematical model creation for cancer chemo-immunotherapy
• Mathematical modeling of regulatory T cell effects on renal cell carcinoma treatment
• Mathematical modeling on helper T cells in a tumor immune system
• Modeling immunotherapy of the tumor -- immune interaction
• Nonlinear dynamics of immunogenic tumors: Parameter estimation and global bifurcation analysis

Cited in

(7)

• Mathematical modeling of tumor-immune system interactions: the effect of rituximab on breast cancer immune response
• How regulatory CD25+CD4+T cells impinge on tumor immunobiology? On the existence of two alternative dynamical classes of tumors
• Optimal T cell cross-reactivity and the role of regulatory T cells
• Studying the importance of regulatory T cells in chemoimmunotherapy mathematical modeling and proposing new approaches for developing a mathematical dynamic of cancer
• Targeting CD4+ T cell exhaustion to improve future immunotherapy strategies
• The dynamics of CD4+ T cell proliferation and regulation
• The role of the cytokines IL-27 and IL-35 in cancer

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