Optimal control model of tumor treatment in the context of cancer stem cell

DOI10.3934/MBE.2022214MaRDI QIDQ2086840zbMATH OpenOpenAlexFDO

Authors Ghassen Haddad, Amira Kebir, N. Raissi, Amira Bouhali, Slimane Ben Miled

Publication date 26 October 2022

Published in Mathematical Biosciences and Engineering (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.3934/mbe.2022214

zbMATH Keywords

Pontryagin's maximum principlecancer stem celloptimal control theorycancer dynamicscytotoxic treatment

Mathematics Subject Classification ID

Medical applications (general) (92C50) Existence theories for optimal control problems involving ordinary differential equations (49J15) Cell biology (92C37)

Cites work

• Mathematical model of adult stem cell regeneration with cross-talk between genetic and epigenetic regulation
• Mathematical modelling of cancer stem cell-targeted immunotherapy
• \textit{BCG} and \(IL-2\) model for bladder cancer treatment with fast and slow dynamics based on SPVF method -- stability analysis

Cited in

(4)

• A \(\beta\)-protein polymerization in Alzheimer disease: optimal control for nucleation parameter estimation
• Optimal vaccination strategies for a heterogeneous population using multiple objectives: the case of \(L_1\)- and \(L_2\)-formulations
• scientific article; zbMATH DE number 682675 (Why is no real title available?)
• Optimal Control of a Cancer Cell Model with Delay

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