Optimal control model of tumor treatment in the context of cancer stem cell

DOI10.3934/MBE.2022214MaRDI QIDQ2086840zbMATH OpenOpenAlexFDO

Authors Ghassen Haddad, Amira Kebir, N. Raissi, Amira Bouhali, Slimane Ben Miled

Publication date 26 October 2022

Published in Mathematical Biosciences and Engineering (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.3934/mbe.2022214

zbMATH Keywords

cancer dynamicscancer stem cellcytotoxic treatmentoptimal control theoryPontryagin's maximum principle

Mathematics Subject Classification ID

Existence theories for optimal control problems involving ordinary differential equations (49J15) Cell biology (92C37) Medical applications (general) (92C50)

Cites work

• \textit{BCG} and \(IL-2\) model for bladder cancer treatment with fast and slow dynamics based on SPVF method -- stability analysis
• Mathematical model of adult stem cell regeneration with cross-talk between genetic and epigenetic regulation
• Mathematical modelling of cancer stem cell-targeted immunotherapy

Cited in

(6)

• Optimal Control of a Cancer Cell Model with Delay
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• A \(\beta\)-protein polymerization in Alzheimer disease: optimal control for nucleation parameter estimation
• Oscillations in a tumor-immune system interaction model with immune response delay
• Unraveling the influence of the objective functional on epidemic optimal control: insights from the SIR model

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