Optimal control model of tumor treatment in the context of cancer stem cell

DOI10.3934/MBE.2022214zbMATH Open1501.92045OpenAlexW4224282793MaRDI QIDQ2086840FDOQ2086840

Authors: Ghassen Haddad, Amira Kebir, N. Raissi, Amira Bouhali, Slimane Ben Miled 

Publication date: 26 October 2022

Published in: Mathematical Biosciences and Engineering (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.3934/mbe.2022214

zbMATH Keywords

Pontryagin's maximum principlecancer stem celloptimal control theorycancer dynamicscytotoxic treatment

Mathematics Subject Classification ID

Medical applications (general) (92C50) Existence theories for optimal control problems involving ordinary differential equations (49J15) Cell biology (92C37)

Cites Work

• Mathematical model of adult stem cell regeneration with cross-talk between genetic and epigenetic regulation
• Mathematical modelling of cancer stem cell-targeted immunotherapy
• \textit{BCG} and \(IL-2\) model for bladder cancer treatment with fast and slow dynamics based on SPVF method -- stability analysis

Cited In (4)

• A \(\beta\)-protein polymerization in Alzheimer disease: optimal control for nucleation parameter estimation
• Optimal vaccination strategies for a heterogeneous population using multiple objectives: the case of \(L_1\)- and \(L_2\)-formulations
• Title not available (Why is that?)
• Optimal Control of a Cancer Cell Model with Delay

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