Mathematical modelling of cancer stem cell-targeted immunotherapy

DOI10.1016/J.MBS.2019.108269MaRDI QIDQ2173873zbMATH OpenOpenAlexWikidataFDO

Authors Daniel Sigal, Michelle Przedborski, Darshan Sivaloganathan, Mohammad Kohandel

Publication date 17 April 2020

Published in Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.mbs.2019.108269

zbMATH Keywords

cancer immunotherapymathematical modelingtumor heterogeneity

Mathematics Subject Classification ID

Qualitative investigation and simulation of ordinary differential equation models (34C60) Medical applications (general) (92C50)

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Cites work

• A mathematical model for single cell cancer\,--\, immune system dynamics
• A mathematical model of cellular immune response to leukemia
• A mathematical model of tumor-immune interactions
• A multicompartment mathematical model of cancer stem cell-driven tumor growth dynamics
• Mathematical model of tumor-immune surveillance
• Mathematical modelling of plasticity and phenotype switching in cancer cell populations
• Modeling immunotherapy of the tumor -- immune interaction
• Modeling the treatment of glioblastoma multiforme and cancer stem cells with ordinary differential equations
• Modelling the immune response to cancer: an individual-based approach accounting for the difference in movement between inactive and activated T cells
• Optimal control in a model of dendritic cell transfection cancer immunotherapy
• Strategies for cancer stem cell elimination: insights from mathematical modeling

Cited in

(16)

• On immunotherapies and cancer vaccination protocols: a mathematical modelling approach
• A mathematical model of treatment of cancer stem cells with immunotherapy
• Mathematical modeling of mutant transferrin-CRM107 molecular conjugates for cancer therapy
• Modeling the stem cell hypothesis: investigating the effects of cancer stem cells and TGF \(- \beta\) on tumor growth
• Optimal control model of tumor treatment in the context of cancer stem cell
• Mathematical modeling of tumor and cancer stem cells treated with CAR-T therapy and inhibition of TGF-\(\beta\)
• Tumor growth modeling via Fokker-Planck equation
• Higher order solitary solutions to the meta-model of diffusively coupled Lotka-Volterra systems
• A minimal model of T cell avidity may identify subtherapeutic vaccine schedules
• Modelling of killer T-cell and cancer cell subpopulation dynamics under immuno- and chemotherapies
• Cancer-induced immunosuppression can enable effectiveness of immunotherapy through bistability generation: a mathematical and computational examination
• Immune evasion through competitive inhibition: the shielding effect of cancer non-stem cells
• Modeling the treatment of glioblastoma multiforme and cancer stem cells with ordinary differential equations
• Extinction models for cancer stem cell therapy
• Modeling the impact of adiponectin on tumor-immune dynamics: stability, bifurcations, and optimal control
• System variable reduction and global sensitivity analysis for a complex model of cancer cell differentiation

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