Uncovering cross-bridge properties that underlie the cardiac active complex modulus using model linearisation techniques

DOI10.1016/J.MBS.2022.108922MaRDI QIDQ2103607zbMATH OpenOpenAlexFDO

Authors Julia H. Musgrave, J. C. Han, Marie-Louise Ward, Andrew J. Taberner, Denis S. Loiselle, Kenneth Tran

Publication date 9 December 2022

Published in Mathematical Biosciences (Search for Journal in Brave)

Copyright license Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International

Full work available at URL https://doi.org/10.1016/j.mbs.2022.108922

zbMATH Keywords

complex moduluscardiac cross-bridge modelcross-bridge strain dependencecrossbridge work productionsarcomere length dependencesinusoidal analysis

Mathematics Subject Classification ID

Physiology (general) (92C30) Biomechanics (92C10) Physiological flow (92C35)

Recommendations

• A simple model of cardiac muscle for multiscale simulation: passive mechanics, crossbridge kinetics and calcium regulation
• scientific article; zbMATH DE number 3945931
• An integrated formulation of anisotropic force-calcium relations driving spatio-temporal contractions of cardiac myocytes
• Active force generation in cardiac muscle cells: mathematical modeling and numerical simulation of the actin-myosin interaction
• Thermodynamically consistent orthotropic activation model capturing ventricular systolic wall thickening in cardiac electromechanics

Cited in

(3)

• Cross-bridge kinetics in myofibrils containing familial hypertrophic cardiomyopathy R58Q mutation in the regulatory light chain of myosin
• In memory of Edmund John Crampin: multi-scale and multi-physics phenomena in biology
• Modelling and disentangling physiological mechanisms: linear and nonlinear identification techniques for analysis of cardiovascular regulation

This page was built for publication: Uncovering cross-bridge properties that underlie the cardiac active complex modulus using model linearisation techniques

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q2103607)