Global stability of SAIRS epidemic models

DOI10.1016/J.NONRWA.2021.103501zbMATH Open1485.92147arXiv2109.05122OpenAlexW4206518192WikidataQ113292587 ScholiaQ113292587MaRDI QIDQ2113895FDOQ2113895

Authors: Stefania Ottaviano, Mattia Sensi, Sara Sottile 

Publication date: 14 March 2022

Published in: Nonlinear Analysis. Real World Applications (Search for Journal in Brave)

Abstract: We study an SAIRS-type epidemic model with vaccination, where the role of asymptomatic and symptomatic infectious individuals are explicitly considered in the transmission patterns of the disease. We provide a global stability analysis for the model. We determine the value of the basic reproduction number $mathcal{R}_0$ and prove that the disease-free equilibrium is globally asymptotically stable if $mathcal{R}_0<1$ and unstable if $mathcal{R}_0>1$, condition under which a positive endemic equilibrium exists. We investigate the global stability of the endemic equilibrium for some variations of the original model under study and answer to an open problem proposed in Ansumali et al. cite{ansumali2020modelling}. In the case of the SAIRS model without vaccination, we prove the global asymptotic stability of the disease-free equilibrium also when $mathcal{R}_0=1$. We provide a thorough numerical exploration of our model, to validate our analytical results.

Full work available at URL: https://arxiv.org/abs/2109.05122

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zbMATH Keywords

vaccinationbasic reproduction numbergeometric approachglobal asymptotic stabilityLyapunov functionssusceptible-asymptomatic infected-symptomatic infected-recovered-susceptible

Mathematics Subject Classification ID

Epidemiology (92D30) Asymptotic properties of solutions to ordinary differential equations (34D05) Stability of solutions to ordinary differential equations (34D20) Global stability of solutions to ordinary differential equations (34D23)

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Cited In (13)

• Threshold dynamics of a viral infection model with defectively infected cells
• A survey on Lyapunov functions for epidemic compartmental models
• Global stability of two epidemic models
• Nonlinear dynamics of an epidemic compartment model with asymptomatic infections and mitigation
• An improved algebraic approach to proving global stability of autonomous polynomial differential systems with applications to epidemic models
• Global stability of multi‐group SAIRS epidemic models
• Threshold dynamics of SAIRS epidemic model with semi‐Markov switching
• A discrete state-structured model on networks with two transmission modes: global dynamics analysis
• Optimal control for dengue transmission based on a model with reinfection and treatment
• Global analysis of an SAIS model
• Global stability of an SAIRS epidemic model with vaccinations, transient immunity and treatment
• Modified SEIR epidemic model including asymptomatic and hospitalized cases with correct demographic evolution
• Dynamics of epidemic models with asymptomatic infection and seasonal succession

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