Parameter estimation for closed-loop lumped parameter models of the systemic circulation using synthetic data

DOI10.1016/J.MBS.2021.108731MaRDI QIDQ2118476zbMATH OpenOpenAlexFDO

Authors Nikolai L. Bjørdalsbakke, Jacob T. Sturdy, David R. Hose, Leif R. Hellevik

Publication date 22 March 2022

Published in Mathematical Biosciences (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.1016/j.mbs.2021.108731

zbMATH Keywords

lumped parameter modelsmathematical optimizationparameter estimationsensitivity analysissystemic circulation

Mathematics Subject Classification ID

Physiological flow (92C35)

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Cites work

• A practical approach to parameter estimation applied to model predicting heart rate regulation
• A sensitivity matrix based methodology for inverse problem formulation
• Computing Forward-Difference Intervals for Numerical Optimization
• On global identifiability for arbitrary model parametrizations
• On identifiability of nonlinear ODE models and applications in viral dynamics
• Parameter estimation in a minimal model of cardio-pulmonary interactions
• Parameter subset selection techniques for problems in mathematical biology
• Practical identifiability and uncertainty quantification of a pulsatile cardiovascular model

Cited in

(12)

• Model-based identification and diagnosis of a porcine model of induced endotoxic shock with hemofiltration
• Estimation and identification of parameters in a lumped cerebrovascular model
• Model-based quantification of left ventricular diastolic function in critically ill patients with atrial fibrillation from routine data: a feasibility study
• Patient-specific parameter estimation: coupling a heart model and experimental data
• Optimal measurement locations for diagnosis of aortic abnormalities in a lumped-parameter model of the systemic circulation using sensitivity analysis
• A method to personalize the lumped parameter model of coronary artery
• Structural correlation method for model reduction and practical estimation of patient specific parameters illustrated on heart rate regulation
• Personalization of electro-mechanical models of the pressure-overloaded left ventricle: fitting of windkessel-type afterload models
• Practical identifiability and uncertainty quantification of a pulsatile cardiovascular model
• Two new calibration techniques of lumped-parameter mathematical models for the cardiovascular system
• A parameter estimation framework for patient-specific hemodynamic computations
• Model-based computation of total stressed blood volume from a preload reduction manoeuvre

Describes a project that uses

Uses Software

• SciPy
• Python

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