Sparse block signal detection and identification for shared cross-trait association analysis

DOI10.1214/21-AOAS1523MaRDI QIDQ2154183zbMATH OpenWikidataFDO

Authors Jianqiao Wang, Wanjie Wang, Hongzhe Li

Publication date 14 July 2022

Published in The Annals of Applied Statistics (Search for Journal in Brave)

zbMATH Keywords

principal component analysispleiotropylocal dependencysparse simultaneous signal

Mathematics Subject Classification ID

Nonparametric hypothesis testing (62G10) Factor analysis and principal components; correspondence analysis (62H25) Applications of statistics to biology and medical sciences; meta analysis (62P10) Protein sequences, DNA sequences (92D20)

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Cites work

• A Geometric Perspective on the Power of Principal Component Association Tests in Multiple Phenotype Studies
• Higher criticism for detecting sparse heterogeneous mixtures.

Cited in

(3)

• On blockwise and reference panel-based estimators for genetic data prediction in high dimensions
• On Genetic Correlation Estimation With Summary Statistics From Genome-Wide Association Studies
• Detection boundary and higher criticism approach for rare and weak genetic effects

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