On the cross-regulation of protein tyrosine phosphatases and receptor tyrosine kinases in intracellular signaling

DOI10.1016/J.JTBI.2004.04.023MaRDI QIDQ2186456zbMATH OpenOpenAlexWikidataFDO

Authors Jason M. Haugh, Ian C. Schneider, Jodee M. Lewis

Publication date 9 June 2020

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2004.04.023

zbMATH Keywords

kinasephosphatasephosphorylationreceptorsignal transduction

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

Recommendations

• Cross-membrane signal transduction of receptor tyrosine kinases (RTKs): from systems biology to systems pharmacology
• A kinetic model of ERK cyclic pathway on substrate control
• Systematic modeling for the insulin signaling network mediated by \(IRS_1\) and \(IRS_2\)
• The kinetics of FGF-2 binding to heparan sulfate proteoglycans and MAP kinase signaling
• Selecting optimal drug-intervention in a pathway involving receptor tyrosine kinases (RTKs)

Cited in

(6)

• Cross-membrane signal transduction of receptor tyrosine kinases (RTKs): from systems biology to systems pharmacology
• Autophosphorylation and the dynamics of the activation of Lck
• Asymptotic states and topological structure of an activation-deactivation chemical network
• Intracellular regulation of cell signaling cascades: how location makes a difference
• A kinetic model of ERK cyclic pathway on substrate control
• The kinetics of FGF-2 binding to heparan sulfate proteoglycans and MAP kinase signaling

This page was built for publication: On the cross-regulation of protein tyrosine phosphatases and receptor tyrosine kinases in intracellular signaling

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q2186456)