Autoimmunity as an immune defense against degenerative processes: a primary mathematical model illustrating the bright side of autoimmunity

DOI10.1016/J.JTBI.2003.11.031MaRDI QIDQ2187600zbMATH OpenOpenAlexWikidataFDO

Authors Uri Nevo, I. Golding, Avidan U. Neumann, Michal Schwartz, Solange Akselrod

Publication date 3 June 2020

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2003.11.031

zbMATH Keywords

autoimmune diseaseautoimmunitymathematical modelmultiple sclerosisneuronal degenerationself-tolerance

Mathematics Subject Classification ID

PDEs in connection with biology, chemistry and other natural sciences (35Q92) Neural biology (92C20) Pathology, pathophysiology (92C32) Control/observation systems governed by functional relations other than differential equations (such as hybrid and switching systems) (93C30)

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• Continuum model of T-cell avidity: understanding autoreactive and regulatory T-cell responses in type 1 diabetes

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