Dynamics of T cell activation threshold tuning

DOI10.1016/j.jtbi.2004.02.002zbMath1439.92061OpenAlexW2080789248WikidataQ47627819 ScholiaQ47627819MaRDI QIDQ2187651

David A. Rand, Hugo Antonius van den Berg

Publication date: 3 June 2020

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2004.02.002

zbMATH Keywords

negative selectionT cell activationTCR signallingT cell tolerancetunable T cell activation threshold

Mathematics Subject Classification ID

Physiology (general) (92C30)

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Cites Work

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• Quantifying the strength of ligand antagonism in TCR triggering
• Antigen presentation on MHC molecules as a diversity filter that enhances immune efficacy
• Thymic Presentation of Autoantigens and the Efficiency of Negative Selection