PER/TIM-mediated amplification, gene dosage effects and temperature compensation in an interlocking-feedback loop model of the \textit{Drosophila} circadian clock

DOI10.1016/j.jtbi.2005.03.030zbMath1445.92016OpenAlexW2166853229WikidataQ48950124 ScholiaQ48950124MaRDI QIDQ2196841

Melinda K. Christensen, Peter Ruoff, Vijay K. Sharma

Publication date: 3 September 2020

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2005.03.030

zbMATH Keywords

\textit{Drosophila}temperature compensation circadian oscillations gene dosage interlocking-feedback loop molecular amplification PDP1 PERIOD TIMELESS VRILLE

Mathematics Subject Classification ID

Biological rhythms and synchronization (92B25)

Related Items (6)

A computational model clarifies the roles of positive and negative feedback loops in the Droso\-phila circadian clock ⋮ Propensity of a circadian clock to adjust to the 24h day-night light cycle and its sensitivity to molecular noise ⋮ Modelling of circadian rhythms in \textit{Drosophila} incorporating the interlocked PER/TIM and VRI/PDP1 feedback loops ⋮ A temperature-compensated model for circadian rhythms that can be entrained by temperature cycles ⋮ A mathematical model of the \textit{Drosophila} circadian clock with emphasis on posttranslational mechanisms ⋮ The Effects of Time-Varying Temperature on Delays in Genetic Networks

Uses Software

LSODE

Cites Work

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