Why a simple model of genetic regulatory networks describes the distribution of avalanches in gene expression data

DOI10.1016/j.jtbi.2007.01.012zbMath1451.92137OpenAlexW2045924769WikidataQ31102340 ScholiaQ31102340MaRDI QIDQ2210068

Alex Graudenzi, Roberto Serra, Marco Villani, Stuart A. Kauffman

Publication date: 5 November 2020

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2007.01.012

zbMATH Keywords

avalanchescell criticalityrandom Boolean networkgene knock-out\textit{S. cerevisiae}genetic network model

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Systems biology, networks (92C42)

Related Items (10)

No tradeoff between versatility and robustness in gene circuit motifs ⋮ Dynamics of unperturbed and noisy generalized Boolean networks ⋮ Dynamical criticality in gene regulatory networks ⋮ Percolation in bipartite Boolean networks and its role in sustaining life ⋮ Stability and structural properties of gene regulation networks with coregulation rules ⋮ On the dynamics of random Boolean networks subject to noise: attractors, ergodic sets and cell types ⋮ The Diffusion of Perturbations in a Model of Coupled Random Boolean Networks ⋮ A divide and conquer method for learning large fuzzy cognitive maps ⋮ Dynamical criticality: overview and open questions ⋮ Dynamical regimes in non-ergodic random Boolean networks

Cites Work

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• Boolean dynamics of networks with scale-free topology
• The modular structure of Kauffman networks
• Genetic network models and statistical properties of gene expression data in knock-out experiments
• Perturbation avalanches and criticality in gene regulatory networks
• Self-organized criticality
• From topology to dynamics in biochemical networks

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