Modeling the intracellular dynamics of the dengue viral infection and the innate immune response

DOI10.1016/J.JTBI.2020.110529MaRDI QIDQ2226004zbMATH OpenOpenAlexWikidataFDO

Authors Mauricio Castaño-Arcila, Luis U. Aguilera, Jesús Rodríguez-González

Publication date 11 February 2021

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2020.110529

zbMATH Keywords

bimodalitybistabilitydengueinnate immune systemintracellular dynamicsISG proteinsstochastic modeling

Mathematics Subject Classification ID

Qualitative investigation and simulation of ordinary differential equation models (34C60) Pathology, pathophysiology (92C32) Cell biology (92C37)

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Cites work

• Control theory and systems biology.
• Mathematical biology. Vol. 1: An introduction.
• Modeling the effect of Tat inhibitors on HIV latency
• Simulation model for dynamics of dengue with innate and humoral immune responses
• Studying HIV latency by modeling the interaction between HIV proteins and the innate immune response

Cited in

(7)

• Simulation model for dynamics of dengue with innate and humoral immune responses
• Mathematical modelling of OAS2 activation by dsRNA and effects of dsRNA lengths
• Using computational approaches to study dengue virus capsid assembly
• Modelling the host immune response to mature and immature dengue viruses
• Dynamics of influenza virus and human host interactions during infection and replication cycle
• Stochastic behavior of within-host progression in primary dengue infection
• Mechanistic modeling explains the dsRNA length-dependent activation of the RIG-I mediated immune response

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