Sensitivity analysis of the reaction occurrence and recurrence times in steady-state biochemical networks

DOI10.1016/J.MBS.2020.108518MaRDI QIDQ2240231zbMATH OpenOpenAlexWikidataFDO

Authors Diego Frezzato

Publication date 8 November 2021

Published in Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.mbs.2020.108518

zbMATH Keywords

completion time statisticscontinuous-time Markov jump processesmaster equationstochastic gene expressionsubstrate inhibition in enzymatic catalysis

Mathematics Subject Classification ID

Applications of continuous-time Markov processes on discrete state spaces (60J28) Biochemistry, molecular biology (92C40) Systems biology, networks (92C42)

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Cites work

• Approximation and inference methods for stochastic biochemical kinetics -- a tutorial review
• scientific article; zbMATH DE number 3806623 (Why is no real title available?)
• Markovian modelling of gene product synthesis
• Quantum noise. A handbook of Markovian and non-Markovian quantum stochastic methods with applications to quantum optics.
• Stationary Markov jump processes in terms of average transition times: setup and some inequalities of kinetic and thermodynamic kind

Cited in

(7)

• Sensitivity of chemical reaction networks: a structural approach. 1. Examples and the carbon metabolic network
• Intrinsic timing in classical master equation dynamics from an extended quadratic format of the evolution law
• Theoretical analysis of time-to-peak responses in biological reaction networks
• Stationary Markov jump processes in terms of average transition times: setup and some inequalities of kinetic and thermodynamic kind
• Sensitivity of Steady States in Networks with Application to Markov Chains and Chemical Reaction Networks
• Sensitivity analysis for stochastic chemical reaction networks with multiple time-scales
• Sensitivity summation theorems for stochastic biochemical reaction systems

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