Predicting the results of competition between two breast cancer lines grown in 3-D spheroid culture

DOI10.1016/J.MBS.2021.108575zbMATH Open1475.92053OpenAlexW3136998408WikidataQ115927452 ScholiaQ115927452MaRDI QIDQ2241925FDOQ2241925

Mehdi Damaghi, Joel S. Brown, Dorothy Wallace, Yan Miao, Audrey Freischel, Marisabel Rodriguez Messan, Robert J. Gillies

Publication date: 9 November 2021

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.mbs.2021.108575

zbMATH Keywords

competitionmathematical modelnumerical simulationcancer cellsMDA-MB-231MCF-7spheroid 3D culture

Mathematics Subject Classification ID

Cell movement (chemotaxis, etc.) (92C17) Pathology, pathophysiology (92C32)

Cites Work

• Title not available (Why is that?)
• The ecology and evolutionary biology of cancer: a review of mathematical models of necrosis and tumor cell diversity
• Mathematical modeling of the proliferation gradient in multicellular tumor spheroids
• Predictive modeling of neuroblastoma growth dynamics in xenograft model after bevacizumab anti-VEGF therapy
• A model for spheroid versus monolayer response of SK-N-SH neuroblastoma cells to treatment with 15-deoxy-\(PGJ_2\)

Cited In (1)

• A simulation of parental and glycolytic tumor phenotype competition predicts observed responses to pH changes and increased glycolysis after anti-VEGF therapy

Uses Software

• Matlab
• Optimization Toolbox

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