Theoretical modeling of collaterally sensitive drug cycles: shaping heterogeneity to allow adaptive therapy

DOI10.1007/s00285-021-01671-6zbMath1475.92093OpenAlexW3205266679WikidataQ113905455 ScholiaQ113905455MaRDI QIDQ2244933

Nikhil Krishnan, Nara Yoon, Jacob G. Scott

Publication date: 12 November 2021

Published in: Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s00285-021-01671-6

Mathematics Subject Classification ID

Medical applications (general) (92C50) Existence theories for free problems in two or more independent variables (49J10)

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Cites Work

• A single-cell approach in modeling the dynamics of tumor microregions
• Optimal therapy scheduling based on a pair of collaterally sensitive drugs
• An elementary approach to modeling drug resistance in cancer
• Modeling continuous levels of resistance to multidrug therapy in cancer