Mathematical model of dynamic protein interactions regulating p53 protein stability for tumor suppression

zbMATH Open1307.92093MaRDI QIDQ2262151FDOQ2262151

Authors: Hua Wang, Guang Peng 

Publication date: 16 March 2015

Published in: Computational \& Mathematical Methods in Medicine (Search for Journal in Brave)

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Mathematics Subject Classification ID

Medical applications (general) (92C50) Biochemistry, molecular biology (92C40)

Cited In (6)

• A computational approach inspired by simulated annealing to study the stability of protein interaction networks in cancer and neurological disorders
• Oncogene-tumor suppressor gene feedback interactions and their control
• Core and specific network markers of carcinogenesis from multiple cancer samples
• Integrative network analysis of cancer cell signaling by high-resolution proteomics
• Modeling hepatitis C virus protein and p53 interactions in hepatocytes: implications for carcinogenesis
• Computational modeling implicates protein scaffolding in p38 regulation of akt

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