Modeling hepatitis C virus protein and p53 interactions in hepatocytes: implications for carcinogenesis

DOI10.1016/J.MBS.2018.10.003zbMATH Open1409.92252OpenAlexW2896746272WikidataQ57480595 ScholiaQ57480595MaRDI QIDQ669129FDOQ669129

Maria I. Poole, Harsh Vardhan Jain, Inmaculada Sorribes

Publication date: 20 March 2019

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.mbs.2018.10.003

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zbMATH Keywords

mathematical modelDNA damageHCVp53FUBP1HCC

Mathematics Subject Classification ID

Epidemiology (92D30) Biochemistry, molecular biology (92C40) Physiology (general) (92C30)

Cites Work

• Mathematical modelling of p53 basal dynamics and DNA damage response
• A Model for p53 Dynamics Triggered by DNA Damage
• A confidence building exercise in data and identifiability: modeling cancer chemotherapy as a case study
• Mathematical model of dynamic protein interactions regulating p53 protein stability for tumor suppression
• Oscillations and DNA repair in a spatio-temporal model of the p53 signalling pathway

Cited In (1)

• A model for hepatocarcinogenesis treating phenotypical changes in focal hepatocellular lesions as epigenetic events

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