Modeling hepatitis C virus protein and p53 interactions in hepatocytes: implications for carcinogenesis

DOI10.1016/J.MBS.2018.10.003MaRDI QIDQ669129zbMATH OpenOpenAlexWikidataFDO

Authors Maria I. Poole, Inmaculada Sorribes, Harsh Vardhan Jain

Publication date 20 March 2019

Published in Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.mbs.2018.10.003

zbMATH Keywords

mathematical modelDNA damageHCVp53FUBP1HCC

Mathematics Subject Classification ID

Epidemiology (92D30) Biochemistry, molecular biology (92C40) Physiology (general) (92C30)

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Cites work

• A Model for p53 Dynamics Triggered by DNA Damage
• A confidence building exercise in data and identifiability: modeling cancer chemotherapy as a case study
• Mathematical model of dynamic protein interactions regulating p53 protein stability for tumor suppression
• Mathematical modelling of p53 basal dynamics and DNA damage response
• Oscillations and DNA repair in a spatio-temporal model of the p53 signalling pathway

Cited in

(2)

• A model for hepatocarcinogenesis treating phenotypical changes in focal hepatocellular lesions as epigenetic events
• Modelling hepatitis C virus infection and the development of hepatocellular carcinoma

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