Segmental aqueous humour outflow and eye orientation have strong influence on ocular drug delivery

DOI10.1016/J.APM.2018.01.007MaRDI QIDQ2295285zbMATH OpenOpenAlexFDO

Authors Chai Y. Loke, Ean Hin Ooi, Mohmed S. Salahudeen, Norlina Ramli, Amir Samsudin

Publication date 12 February 2020

Published in Applied Mathematical Modelling (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.apm.2018.01.007

zbMATH Keywords

pharmacokineticsglaucomaaqueous humor hydrodynamicsophthalmic drugstopical eye drops

Mathematics Subject Classification ID

Medical applications (general) (92C50) Physiological flow (92C35)

Recommendations

• Computational modeling of drug distribution in the posterior segment of the eye: effects of device variables and positions
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• Numerical simulation of aqueous humor flow: from healthy to pathologic situations
• Relationship between saccadic eye movements and formation of the Krukenberg's spindle -- a CFD study

Cites work

• Drug delivery: from a contact lens to the anterior chamber
• Numerical simulation of aqueous humor flow: from healthy to pathologic situations

Cited in

(5)

• Relationship between saccadic eye movements and formation of the Krukenberg's spindle -- a CFD study
• Drug delivery from ophthalmic lenses
• A mathematical model for NIR light protocol optimization in controlled transdermal drug delivery
• Computational modeling of drug distribution in the posterior segment of the eye: effects of device variables and positions
• Aqueous humor dynamics in human eye: a lattice Boltzmann study

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