Randomized phase III oncology trials: a survey and empirical Bayes inference

DOI10.1007/S42519-019-0049-4MaRDI QIDQ2321782zbMATH OpenOpenAlexWikidataFDO

Authors Changyu Shen, Huiping Xu

Publication date 23 August 2019

Published in Journal of Statistical Theory and Practice (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/s42519-019-0049-4

zbMATH Keywords

clinical trialsempirical Bayesoncologyefficacyphase III

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sampling theory, sample surveys (62D05)

Recommendations

• Bayesian Approaches to Randomized Trials
• The estimated and theoretical assurances and the probabilities of launching a phase III trial
• Is the FDA too conservative or too aggressive?: a Bayesian decision analysis of clinical trial design
• A Bayesian Approach to the Design of Phase II Clinical Trials
• Handbook of statistics in clinical oncology

Cites work

• scientific article; zbMATH DE number 3124366 (Why is no real title available?)
• scientific article; zbMATH DE number 708500 (Why is no real title available?)
• Bayesian statistics and the efficiency and ethics of clinical trials
• Empirical Bayes deconvolution estimates
• Inference and missing data
• Optimal Rates of Convergence for Deconvolving a Density
• Parametric Empirical Bayes Inference: Theory and Applications

Cited in

(5)

• Review of Statistical Treatment for Oncology Dose-Escalation Trial with Prolonged Evaluation Window or Fast Enrollment
• Bayesian phase I/II adaptively randomized oncology trials with combined drugs
• The estimated and theoretical assurances and the probabilities of launching a phase III trial
• P-hacking in clinical trials and how incentives shape the distribution of results across phases
• A fiducial approach to the nonparametric deconvolution problem: the discrete case

Describes a project that uses

Uses Software

• bootstrap

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