Novel harmonic regularization approach for variable selection in Cox's proportional hazards model
Summary: Variable selection is an important issue in regression and a number of variable selection methods have been proposed involving nonconvex penalty functions. In this paper, we investigate a novel harmonic regularization method, which can approximate nonconvex \(Lq(1 / 2 < q < 1)\) regularizations, to select key risk factors in the Cox's proportional hazards model using microarray gene expression data. The harmonic regularization method can be efficiently solved using our proposed direct path seeking approach, which can produce solutions that closely approximate those for the convex loss function and the nonconvex regularization. Simulation results based on the artificial datasets and four real microarray gene expression datasets, such as real diffuse large B-cell lymphoma (DCBCL), the lung cancer, and the AML datasets, show that the harmonic regularization method can be more accurate for variable selection than existing Lasso series methods.
- Tuning parameter selection in Cox proportional hazards model with a diverging number of parameters
- Adaptive Lasso for Cox's proportional hazards model
- Variable selection for Cox's proportional hazards model and frailty model
- Elastic SCAD variable selection and its application in Cox model
- A note on path-based variable selection in the penalized proportional hazards model
- Adaptive Lasso for Cox's proportional hazards model
- Analysis of multi-stage convex relaxation for sparse regularization
- scientific article; zbMATH DE number 5957506 (Why is no real title available?)
- scientific article; zbMATH DE number 845714 (Why is no real title available?)
- scientific article; zbMATH DE number 3385132 (Why is no real title available?)
- L 1/2 regularization
- Least angle regression. (With discussion)
- Nearly unbiased variable selection under minimax concave penalty
- Optimally sparse representation in general (nonorthogonal) dictionaries via ℓ 1 minimization
- Partial likelihood
- Piecewise linear regularized solution paths
- Regression modeling strategies. With applications to linear models, logistic regression and survival analysis
- Regularization and Variable Selection Via the Elastic Net
- Sparse Logistic Regression with Lp Penalty for Biomarker Identification
- SparseNet: coordinate descent with nonconvex penalties
- Uncertainty principles and ideal atomic decomposition
- Variable Selection via Nonconcave Penalized Likelihood and its Oracle Properties
- Tuning parameter selection in Cox proportional hazards model with a diverging number of parameters
- A real survival analysis application via variable selection methods for Cox's proportional hazards model
- Cox regression with exclusion frequency-based weights to identify neuroimaging markers relevant to Huntington's disease onset
- A regularized variable selection procedure in additive hazards model with stratified case-cohort design
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