Costs versus benefits: best possible and best practical treatment regimens for HIV

DOI10.1007/S00285-006-0059-1zbMATH Open1115.92030OpenAlexW2005646672WikidataQ51925691 ScholiaQ51925691MaRDI QIDQ2373250FDOQ2373250

Authors: Olga Krakovska, Lindi M. Wahl 

Publication date: 17 July 2007

Published in: Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s00285-006-0059-1

Recommendations

• Optimal drug treatment regimens for HIV depend on adherence
• An optimal strategy for HIV multitherapy
• Drug-sparing regimens for HIV combination therapy: Benefits predicted for ``drug coasting
• Optimal control for HIV treatment
• Optimal multi-therapeutic HIV treatment using a global optimal switching scheme
• Optimal HIV treatment by maximising immune response
• Optimal resource allocation for HIV prevention and control
• Dynamic multidrug therapies for HIV: Optimal and STI control approaches
• Optimal controls of the highly active antiretroviral therapy
• Optimal therapy regimens for treatment-resistent mutations of HIV

zbMATH Keywords

HAARTOptimizationMathematical modelResistanceDrug treatmentHuman immunodeficiency virusSide effects

Mathematics Subject Classification ID

Medical applications (general) (92C50) Applications of optimal control and differential games (49N90) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

Cites Work

• Title not available (Why is that?)
• Optimal control of the chemotherapy of HIV
• Predicting differential responses to structured treatment interruptions during HAART
• Dynamic multidrug therapies for HIV: Optimal and STI control approaches
• HIV dynamics: Modeling, data analysis, and optimal treatment protocols
• Title not available (Why is that?)
• Optimal control of an HIV immunology model
• Optimal HIV treatment by maximising immune response
• A model for treatment strategy in the chemotherapy of AIDS
• Stochastic optimal therapy for enhanced immune response
• Title not available (Why is that?)

Cited In (11)

• Mathematical analysis of an HIV model with impulsive antiretroviral drug doses
• Multiobjective optimal control of HIV dynamics
• Kinetic model of HIV infection including hematopoietic progenitor cells
• The evaluation and prediction model of the effect of AIDS therapy
• Explicitly accounting for antiretroviral drug uptake in theoretical HIV models predicts long-term failure of protease-only therapy
• Treatment monitoring of HIV-infected patients based on mechanistic models
• Optimal drug treatment regimens for HIV depend on adherence
• Optimal control of HIV dynamic using embedding method
• Drug-sparing regimens for HIV combination therapy: Benefits predicted for ``drug coasting
• A model incorporating combined RTIs and PIs therapy during early HIV-1 infection
• Optimal therapy regimens for treatment-resistent mutations of HIV

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