Drug-sparing regimens for HIV combination therapy: Benefits predicted for ``drug coasting

DOI10.1007/s11538-007-9234-9zbMath1245.92031OpenAlexW2039396792WikidataQ51912232 ScholiaQ51912232MaRDI QIDQ2426381

Lindi M. Wahl, Olga Krakovska

Publication date: 22 April 2008

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s11538-007-9234-9

zbMATH Keywords

structured treatment interruptionsdrug resistanceHAARTtoxicitytriple-drug therapy

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Medical applications (general) (92C50)

Related Items (6)

Modeling HIV persistence, the latent reservoir, and viral blips ⋮ Within-host virus models with periodic antiviral therapy ⋮ A MATHEMATICAL MODEL FOR THE TREATMENT OF AIDS-RELATED KAPOSI'S SARCOMA ⋮ Continuous approximation of linear impulsive systems and a new form of robust stability ⋮ Mathematical analysis of an HIV model with impulsive antiretroviral drug doses ⋮ Predictive models for maximum recommended therapeutic dose of antiretroviral drugs

Cites Work

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• Predicting differential responses to structured treatment interruptions during HAART
• Optimal control of the chemotherapy of HIV
• A model for treatment strategy in the chemotherapy of AIDS
• Optimal drug treatment regimens for HIV depend on adherence
• Costs versus benefits: best possible and best practical treatment regimens for HIV
• Mathematical Analysis of HIV-1 Dynamics in Vivo

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