A mathematical analysis of SELEX

DOI10.1016/J.COMPBIOLCHEM.2006.10.002MaRDI QIDQ2373271zbMATH OpenOpenAlexWikidataFDO

Authors Howard A. Levine, Marit Nilsen-Hamilton

Publication date 17 July 2007

Published in Computational Biology and Chemistry (Search for Journal in Brave)

Full work available at URL http://europepmc.org/articles/pmc2374838

zbMATH Keywords

Aptamer

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Dynamical systems in biology (37N25) Computational methods for problems pertaining to biology (92-08) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

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Cited in

(9)

• Theoretical consideration of selective enrichment in in vitro selection: optimal concentration of target molecules
• Estimation of statistical binding properties of ligand population during in vitro selection based on population dynamics theory
• A model for sequential evolution of ligands by exponential enrichment (SELEX) data
• High affinity extremes in combinatorial libraries and repertoires
• A discrete dynamical system arising in molecular biology
• A computational study of alternate SELEX
• A mathematical analysis of multiple-target SELEX
• Discrete dynamical systems in multiple target and alternate SELEX
• Mathematical consideration of massive estimation of dissociation rate constant for genotype-phenotype linking molecules bound to targets through washing/selection and next-generation sequencing

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