A contact process with mutations on a tree

DOI10.1016/J.SPA.2007.04.007MaRDI QIDQ2476882zbMATH OpenOpenAlexFDO

Authors Thomas M. Liggett, Rinaldo Schinazi, Jason Schweinsberg

Publication date 12 March 2008

Published in Stochastic Processes and their Applications (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/math/0612564

zbMATH Keywords

branching processcontact processimmune systemmutationspatial stochastic model

Mathematics Subject Classification ID

Interacting random processes; statistical mechanics type models; percolation theory (60K35)

Abstract: Consider the following stochastic model for immune response. Each pathogen gives birth to a new pathogen at rate $lambda$. When a new pathogen is born, it has the same type as its parent with probability $1-r$. With probability $r$, a mutation occurs, and the new pathogen has a different type from all previously observed pathogens. When a new type appears in the population, it survives for an exponential amount of time with mean 1, independently of all the other types. All pathogens of that type are killed simultaneously. Schinazi and Schweinsberg (2006) have shown that this model on $$ behaves rather differently from its non-spatial version. In this paper, we show that this model on a homogeneous tree captures features from both the non-spatial version and the $$ version. We also obtain comparison results between this model and the basic contact process on general graphs.

Review text

Here the authors study evolution of the following branching process: a pathogen gives birth to a new pathogen at rate \(\lambda\). When a new pathogen is born, it has the same type as its parent with probability \(1-r\). The new pathogen has a different type with probability \(r\). A new type survives for an exponential amount of time with mean 1. All pathogens of that type are killed simultaneously. The authors show that this model for immune response captures features from spatial and non-spatial versions. Conditions on \(\lambda\) and \(r\) under which the process dies or survives are obtained.

Recommendations

• A branching process for virus survival
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Cites work

• Contact interactions on a lattice
• scientific article; zbMATH DE number 1350307 (Why is no real title available?)
• scientific article; zbMATH DE number 3892344 (Why is no real title available?)
• On the spread of viruses on the Internet
• Spatial and non-spatial stochastic models for immune response
• The contact process on trees
• Thresholds for virus spread on networks

Cited in

(9)

• Epidemic models with immunization and mutations on a finite population
• T. E. Harris' contributions to interacting particle systems and percolation
• Contact Process with Destruction of Cubes and Hyperplanes: Forest Fires Versus Tornadoes
• Spatial and non-spatial stochastic models for immune response
• Stochastic models for large interacting systems and related correlation inequalities
• Scaling limit of an adaptive contact process
• Survival of a single mutant in one dimension
• A contact process with stronger mutations on trees
• The structure of the allelic partition of the total population for Galton-Watson processes with neutral mutations

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