A hidden Markov model with molecular mechanics energy-scoring function for transmembrane helix prediction

DOI10.1016/J.COMPBIOLCHEM.2004.07.002MaRDI QIDQ2490540zbMATH OpenOpenAlexDBLPWikidataFDO

Authors W. Jim Zheng, Velin Z. Spassov, Lisa Yan, Paul K. Flook, Sándor Szalma

Publication date 16 May 2006

Published in Computational Biology and Chemistry (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.compbiolchem.2004.07.002

zbMATH Keywords

Folding energyGPCRHidden Markov modelTopology predictionTransmembrane protein topology

Mathematics Subject Classification ID

Applications of Markov chains and discrete-time Markov processes on general state spaces (social mobility, learning theory, industrial processes, etc.) (60J20) Cell biology (92C37) Biochemistry, molecular biology (92C40)

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Cites work

• ConPred\_elite: a highly reliable approach to transmembrane topology prediction

Cited in

(4)

• Modeling and predicting all- transmembrane proteins including helix-helix pairing
• Scoring hidden Markov models to discriminate \(\beta\)-barrel membrane proteins
• ConPred\_elite: a highly reliable approach to transmembrane topology prediction
• Improving Prediction of Hydrophobic Segments along a Transmembrane Protein Sequence using Adaptive Multiscale Lifting

Describes a project that uses

Uses Software

• CHARMM

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