Mathematical model of an antiretroviral therapy to HIV via Filippov theory

DOI10.1016/J.AMC.2020.125179MaRDI QIDQ2660108zbMATH OpenOpenAlexFDO

Authors Daniel Chieregato Vicentin, L. F. Gonçalves, Paulo F. A. Mancera, Tiago de Carvalho

Publication date 29 March 2021

Published in Applied Mathematics and Computation (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.amc.2020.125179

zbMATH Keywords

antiretroviral therapiesHIVintermittent treatmentpiecewise smooth vector fieldstypical singularities

Mathematics Subject Classification ID

Discontinuous ordinary differential equations (34A36) Topological structure of integral curves, singular points, limit cycles of ordinary differential equations (34C05) Qualitative investigation and simulation of ordinary differential equation models (34C60) Control problems involving ordinary differential equations (34H05) Medical epidemiology (92C60)

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Cites work

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• The double scroll family
• The Two-Fold Singularity of Discontinuous Vector Fields

Cited in

(11)

• Isochronous attainable manifolds for piecewise smooth dynamical systems
• Global dynamics for a Filippov system with media effects
• A piecewise model of virus-immune system with effector cell-guided therapy
• Sliding mode control in a mathematical model to chemoimmunotherapy: the occurrence of typical singularities
• The local behavior around switching planes in a mathematical model to chemoimmunotherapy
• Investigating the effect of pyroptosis on the slow CD4+ T cell depletion in HIV-1 infection, by dynamical analysis of its discontinuous mathematical model
• Planar quartic-quadratic fold-fold singularity of Filippov systems and its bifurcation
• Integrable 2D and 3D piecewise smooth vector fields with chaotic behavior and preserving energy or not
• Beyond the Bristol book: advances and perspectives in non-smooth dynamics and applications
• A joint-threshold Filippov model describing the effect of intermittent androgen-deprivation therapy in controlling prostate cancer
• Bifurcations analysis of a 3D Filippov pest-natural enemy system with stage structure for the prey

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