An adaptive randomized design with application to estimation

DOI10.2307/3316054zbMath1013.62082OpenAlexW1973353515MaRDI QIDQ2738924

Vincent F. Melfi, Connie Page, Margarida Geraldes

Publication date: 6 March 2002

Published in: Canadian Journal of Statistics (Search for Journal in Brave)

Full work available at URL: https://semanticscholar.org/paper/250050b85876b83a75b1536b7546cc870c932c10

zbMATH Keywords

randomizationmartingale convergence theoremmartingale central limit theoremadaptive allocation

Mathematics Subject Classification ID

Design of statistical experiments (62K99) Central limit and other weak theorems (60F05) Sequential statistical design (62L05)

Related Items (27)

A simple solution to the inadequacy of asymptotic likelihood-based inference for response-adaptive clinical trials: likelihood-based inference for RAR trials ⋮ Asymptotic properties of doubly adaptive biased coin designs for multitreatment clinical trials. ⋮ Goodness-of-fit test for response adaptive clinical trials ⋮ An optimal response-adaptive design with dual constraints ⋮ Randomly Reinforced Urn Designs with Prespecified Allocations ⋮ Sequential and Two-Stage Fixed-Width Confidence Interval Estimation in Response-Adaptive Designs ⋮ Interval estimation for response adaptive clinical trials ⋮ An optimal allocation for response-adaptive designs ⋮ Statistical properties of two-color randomly reinforced urn design targeting fixed allocations ⋮ Asymptotically efficient estimation in response adaptive trials ⋮ On binary longitudinal mixed models in adaptive clinical trials ⋮ Independence after adaptive allocation ⋮ Adaptive Designs to Maximize Power in Clinical Trials with Multiple Treatments ⋮ Multi-objective optimal designs in comparative clinical trials with covariates: the reinforced doubly adaptive biased coin design ⋮ Optimal Adaptive Designs for Binary Response Trials ⋮ Asymptotic results on a class of adaptive multi-treatment designs ⋮ An urn model to construct an efficient test procedure for response adaptive designs ⋮ Response-adaptive designs for continuous outcomes ⋮ Statistical Inference of Adaptive Designs with Binary Responses ⋮ On a two-treatment adaptive allocation rule for continuous response ⋮ On the Large Sample Optimality of Sequential Designs for Comparing Two or More Treatments ⋮ Two-treatment covariate-dependent response adaptive allocation design for dichotomous response ⋮ Implementing optimal allocation in clinical trials with multiple endpoints ⋮ Response‐Adaptive Randomization for Clinical Trials with Continuous Outcomes ⋮ Estimation after adaptive allocation ⋮ On the almost sure convergence of adaptive allocation procedures ⋮ A response-adaptive design in crossover trial

Cites Work

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• The analysis of sequential experiments with feedback to subjects
• The adaptive biased coin design for sequential experiments
• The doubly adaptive biased coin design for sequential clinical trials
• Estimation after adaptive allocation
• Central limit theorems for doubly adaptive biased coin designs
• Design for the Control of Selection Bias
• Sequential Tests Involving Two Populations
• A Sequential Analogue of the Behrens-Fisher Problem
• Forcing a sequential experiment to be balanced

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