Mathematically-optimized magnetic resonance spectroscopy in breast cancer diagnostics: implications for personalized cancer medicine

DOI10.1007/S10910-015-0556-9MaRDI QIDQ283219zbMATH OpenOpenAlexFDO

Authors Dževad Belkić, Karen Belkić

Publication date 13 May 2016

Published in Journal of Mathematical Chemistry (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/s10910-015-0556-9

zbMATH Keywords

breast cancer diagnosticsmagnetic resonance spectroscopymathematical optimizationpersonalized cancer medicinefast Padé transform

Mathematics Subject Classification ID

Medical applications (general) (92C50) Biomedical imaging and signal processing (92C55)

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Cites work

• Automatic self-correcting in signal processing for magnetic resonance spectroscopy: noise reduction, resolution improvement and splitting overlapped peaks
• Exact quantification of time signals from magnetic resonance spectroscopy by the fast Padé transform with applications to breast cancer diagnostics
• How the fast Padé transform handles noise for MRS data from the ovary: importance for ovarian cancer diagnostics
• Magnetic resonance spectroscopy with high-resolution and exact quantification in the presence of noise for improving ovarian cancer detection
• Mathematical modeling of an NMR chemistry problem in ovarian cancer diagnostics
• Mathematical optimization of in vivo NMR chemistry through the fast Padé transform: Potential relevance for early breast cancer detection by magnetic resonance spectroscopy
• Padé optimization of noise-corrupted magnetic resonance spectroscopic time signals from fibroadenoma of the breast
• Quantum-mechanical signal processing and spectral analysis.
• Resolution enhancement as a key step towards clinical implementation of Padé-optimized magnetic resonance spectroscopy for diagnostic oncology
• The potential for practical improvements in cancer diagnostics by mathematically-optimized magnetic resonance spectroscopy
• Unequivocal disentangling genuine from spurious information in time signals: clinical relevance in cancer diagnostics through magnetic resonance spectroscopy
• Unequivocal resolution of multiplets in MR spectra for prostate cancer diagnostics achieved by the fast Padé transform

Cited in

(19)

• Encoded in vivo time signals from the ovary in magnetic resonance spectroscopy: poles and zeros as the cornerstone for stability of response functions of systems to external perturbations
• Synergism of spectra averaging and extrapolation for quantification of in vivo MRS time signals encoded from the ovary
• Visualizing hidden components of envelopes non-parametrically in magnetic resonance spectroscopy: phosphocholine, a breast cancer biomarker
• In vitro proton magnetic resonance spectroscopy at 14T for benign and malignant ovary. I: Signal processing by the nonparametric fast Padé transform
• Exact quantification by the nonparametric fast Padé transform using only shape estimation of high-order derivatives of envelopes
• Improving the diagnostic yield of magnetic resonance spectroscopy for pediatric brain tumors through mathematical optimization
• Validation of reconstructed component spectra from non-parametric derivative envelopes: comparison with component lineshapes from parametric derivative estimations with the solved quantification problem
• Explicit extraction of absorption peak positions, widths and heights using higher order derivatives of total shape spectra by nonparametric processing of time signals as complex damped multi-exponentials
• The fast Padé transform for noisy magnetic resonance spectroscopic data from the prostate: potential contribution to individualized prostate cancer care
• How the fast Padé transform handles noise for MRS data from the ovary: importance for ovarian cancer diagnostics
• Quantification by the fast Padé transform of magnetic resonance spectroscopic data encoded at 1.5 T: implications for brain tumor diagnostics
• Padé optimization of noise-corrupted magnetic resonance spectroscopic time signals from fibroadenoma of the breast
• In vivo magnetic resonance spectroscopy for ovarian cancer diagnostics: quantification by the fast Padé transform
• Robust identification of the cancer biomarker phosphocholine through partitioned envelopes in noisy magnetic resonance spectroscopic data by the non-parametric fast Padé transform
• Mathematical optimization of in vivo NMR chemistry through the fast Padé transform: Potential relevance for early breast cancer detection by magnetic resonance spectroscopy
• Review of recent applications of the conventional and derivative fast Padé transform for magnetic resonance spectroscopy
• Magnetic resonance spectroscopy with high-resolution and exact quantification in the presence of noise for improving ovarian cancer detection
• Automatic self-correcting in signal processing for magnetic resonance spectroscopy: noise reduction, resolution improvement and splitting overlapped peaks
• Iterative averaging of spectra as a powerful way of suppressing spurious resonances in signal processing

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