Design and Estimation for Evaluating Principal Surrogate Markers in Vaccine Trials

DOI10.1111/biom.12014zbMath1274.62794WikidataQ39467318 ScholiaQ39467318MaRDI QIDQ2846433

Julian Wolfson, Ying Huang, Peter B. Gilbert

Publication date: 5 September 2013

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc3713795

zbMATH Keywords

two-phase sampling design; pseudo-score; estimated likelihood; principal surrogate; closeout placebo vaccination; immune correlate

Mathematics Subject Classification ID

62P10: Applications of statistics to biology and medical sciences; meta analysis

Related Items

A unified evaluation of differential vaccine efficacy, Predicting overall vaccine efficacy in a new setting by re-calibrating baseline covariate and intermediate response endpoint effect modifiers of type-specific vaccine efficacy, Sensitivity analysis for evaluating principal surrogate endpoints relaxing the equal early clinical risk assumption, Evaluating principal surrogate markers in vaccine trials in the presence of multiphase sampling

Cites Work

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