A parametric model for analyzing anticipation in genetically predisposed families

DOI10.2202/1544-6115.1424zbMATH Open1276.92062OpenAlexW1977688865WikidataQ83986665 ScholiaQ83986665MaRDI QIDQ2864081FDOQ2864081

Authors: Klaus Larsen, Janne Petersen, Inge Bernstein, Mef Nilbert 

Publication date: 5 December 2013

Published in: Statistical Applications in Genetics and Molecular Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.2202/1544-6115.1424

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zbMATH Keywords

clustercompeting risksright censoringsurvival analysishereditary cancerHNPCCLynch syndrome

Mathematics Subject Classification ID

Medical applications (general) (92C50) Genetics and epigenetics (92D10) Testing in survival analysis and censored data (62N03)

Cited In (3)

• Testing for Age‐at‐Onset Anticipation with Affected Parent‐Child Pairs
• Bayesian modeling for genetic anticipation in presence of mutational heterogeneity: a case study in Lynch syndrome
• Predicting disease onset from mutation status using proband and relative data with applications to Huntington's disease

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