A parametric model for analyzing anticipation in genetically predisposed families

DOI10.2202/1544-6115.1424MaRDI QIDQ2864081zbMATH OpenOpenAlexWikidataFDO

Authors Klaus Larsen, Janne Petersen, Inge Bernstein, Mef Nilbert

Publication date 5 December 2013

Published in Statistical Applications in Genetics and Molecular Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.2202/1544-6115.1424

zbMATH Keywords

clustercompeting risksright censoringsurvival analysishereditary cancerHNPCCLynch syndrome

Mathematics Subject Classification ID

Medical applications (general) (92C50) Genetics and epigenetics (92D10) Testing in survival analysis and censored data (62N03)

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Cited in

(3)

• Predicting disease onset from mutation status using proband and relative data with applications to Huntington's disease
• Bayesian modeling for genetic anticipation in presence of mutational heterogeneity: a case study in Lynch syndrome
• Testing for Age‐at‐Onset Anticipation with Affected Parent‐Child Pairs

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