Estimating genetic association parameters from family data

DOI10.1093/BIOMET/91.1.219MaRDI QIDQ5456564zbMATH OpenOpenAlexFDO

Authors Alice S. Whittemore

Publication date 8 April 2008

Published in Biometrika (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1093/biomet/91.1.219

zbMATH Keywords

constrained optimisationgenetic associationnuclear familyrelative risk estimation

Mathematics Subject Classification ID

Nonparametric estimation (62G05) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Recommendations

• Family-based association tests using genotype data with uncertainty
• Estimation Problems in Fitting Genetic Models to Familial Data
• Testing and Estimating Gene-Environment Interactions in Family-Based Association Studies
• Interval estimation of familial correlations from pedigrees
• Exponential family models and statistical genetics
• On the validity of within-nuclear-family genetic association analysis in samples of extended families
• The role of family-based designs in genome-wide association studies
• Maximum likelihood estimation of familial correlations
• Family-based association studies

Cited in

(18)

• A parametric model for analyzing anticipation in genetically predisposed families
• Unbiased and locally efficient estimation of genetic effect on quantitative trait in the presence of population admixture
• A Measure of partial association between disease and genotype for the two-parent problem
• Comparing estimates of genetic variance across different relationship models
• A doubly robust test for gene-environment interaction in family-based studies of affected offspring
• Testing and Estimating Gene-Environment Interactions in Family-Based Association Studies
• Locally-efficient robust estimation of haplotype-disease association in family-based studies
• Robust Estimation of Gene Frequency and Association Parameters
• Parametric Estimation in a Genetic Mixture Model with Application to Nuclear Family Data
• Covariate adaptive familywise error rate control for genome-wide association studies
• A statistical method for joint estimation of cis‐eQTLs and parent‐of‐origin effects under family trio design
• \texttt{Polyunphased}: an extension to polytomous outcomes of the unphased package for family-based genetic association analysis
• A Method for Estimating Penetrance from Families Sampled for Linkage Analysis
• Allele-sharing among affected relatives: non-parametric methods for identifying genes
• A multivariate family-based association test using generalized estimating equations: FBAT-GEE
• 7. Categorical Data Analysis
• On the validity of within-nuclear-family genetic association analysis in samples of extended families
• Bivariate traits association analysis using generalized estimating equations in family data

This page was built for publication: Estimating genetic association parameters from family data

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q5456564)