Robust Estimation of Gene Frequency and Association Parameters

DOI10.2307/2532781MaRDI QIDQ4842859zbMATH OpenOpenAlexWikidataFDO

Authors Jane M. Olson

Publication date 18 October 1995

Published in Biometrics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.2307/2532781

zbMATH Keywords

allele frequency estimationassociation parametersconsistent estimatesgene frequenceygeneralized estimating equationsgenetic disequilibriaHardy-Weinberg disequilibrium parameterslinkage equilibriummarginal modelmaximum likelihood methodstesting for marker-disease associationtesting of linkage

Mathematics Subject Classification ID

Robustness and adaptive procedures (parametric inference) (62F35) Applications of statistics to biology and medical sciences; meta analysis (62P10) Genetics and epigenetics (92D10)

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Cited in

(12)

• Effective sample size: quick estimation of the effect of related samples in genetic case-control association analyses
• Some statistical properties of efficiency robust tests with applications to genetic association studies
• Sample size and power analysis for sparse signal recovery in genome-wide association studies
• Estimation Problems in Fitting Genetic Models to Familial Data
• Bias-reduced estimators and confidence intervals for odds ratios in genome-wide association studies
• Best Linear Unbiased Allele-Frequency Estimation in Complex Pedigrees
• Estimation of gene/haplotype frequencies in genetic marker systems based on phenotype data
• Estimation of parameters under hardy-weinberg law in population genetics
• Robust k-mer frequency estimation using gapped k-mers
• A Minimum Distance Estimation Approach to Estimate the Recombination Fraction from a Marker Locus in Robust Linkage Analysis for Quantitative Traits
• ROBUST NON-PARAMETRIC ESTIMATION OF GENOTYPE-PHENOTYPE RELATIONSHIPS IN HUMAN PEDIGREES
• Maximizing a Family of Optimal Statistics over a Nuisance Parameter with Applications to Genetic Data Analysis

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