A Method for Estimating Penetrance from Families Sampled for Linkage Analysis

DOI10.1111/J.1541-0420.2006.00614.XMaRDI QIDQ5295367zbMATHOpenAlexWikidataFDO

Authors Yuanjia Wang, Ruth Ottman, Daniel Rabinowitz

Publication date 27 July 2007

Published in Biometrics (Search for Journal in Brave)

Full work available at URL http://europepmc.org/articles/pmc1839037

zbMATH Keywords

riskepilepsyage at onsetBayes formula

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Genetics and epigenetics (92D10)

Recommendations

• Estimating genetic association parameters from family data
• A marginal likelihood approach for estimating penetrance from kin-cohort designs
• Statistical inference on the penetrances of rare genetic mutations based on a case-family design
• Determining Inheritance Distributions via Stochastic Penetrances
• Interval estimation of familial correlations from pedigrees
• Estimation of linkage and association from allele transmission data
• Effects of violations of assumptions on likelihood methods for estimating the penetrance of an autosomal dominant mutation from kin-cohort studies.

Cited in

(2)

• Statistical inference on the penetrances of rare genetic mutations based on a case-family design
• Population-Calibrated Gene Characterization

This page was built for publication: A Method for Estimating Penetrance from Families Sampled for Linkage Analysis

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q5295367)