Estimation of selection intensity under overdominance by Bayesian methods

DOI10.2202/1544-6115.1466zbMATH Open1276.92050OpenAlexW1971494194WikidataQ33817279 ScholiaQ33817279MaRDI QIDQ2864089FDOQ2864089

Authors: Paul Joyce, Zaid Abdo, Erkan Ozge Buzbas 

Publication date: 5 December 2013

Published in: Statistical Applications in Genetics and Molecular Biology (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc2861324

Recommendations

• Maximum likelihood and Bayesian methods for estimating the distribution of selective effects among classes of mutations using DNA polymorphism data
• Inference on the strength of balancing selection for epistatically interacting loci
• Inference on the strength of balancing selection for epistatically interacting loci
• Bayesian inference of selection in the Wright-Fisher diffusion model
• Maximum likelihood estimates under \(k\)-allele models with selection can be numerically unstable

zbMATH Keywords

Bayesian inferenceoverdominanceheterozygote advantagebalancing selection \(k\)-allele models

Mathematics Subject Classification ID

Bayesian inference (62F15) Applications of statistics to biology and medical sciences; meta analysis (62P10) Genetics and epigenetics (92D10)

Cited In (8)

• Inference on the strength of balancing selection for epistatically interacting loci
• Inference from the stationary distribution of allele frequencies in a family of Wright-Fisher models with two levels of genetic variability
• Inference on the strength of balancing selection for epistatically interacting loci
• Padé approximants and exact two-locus sampling distributions
• Maximum likelihood and Bayesian methods for estimating the distribution of selective effects among classes of mutations using DNA polymorphism data
• A novel spectral method for inferring general diploid selection from time series genetic data
• Bayesian inference of selection in the Wright-Fisher diffusion model
• Allele frequencies and selection coefficients in locally adapted populations

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