Computing rates of Markov models of voltage-gated ion channels by inverting partial differential equations governing the probability density functions of the conducting and non-conducting states
DOI10.1016/J.MBS.2016.04.011zbMATH Open1358.92046OpenAlexW2345853117WikidataQ39787637 ScholiaQ39787637MaRDI QIDQ288961FDOQ288961
Authors: Aslak Tveito, Glenn Terje Lines, Andrew G. Edwards, Andrew D. McCulloch 
Publication date: 27 May 2016
Published in: Mathematical Biosciences (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1016/j.mbs.2016.04.011
Recommendations
- A Markov chain inversion approach to identify the transition rates of ion channels
- Bayesian inference for ion–channel gating mechanisms directly from single–channel recordings, using Markov chain Monte Carlo
- Markov models for ion channels: versatility versus identifiability and speed
- Determining transition rates of ionic channels via observation
- Statistical properties of ion channel records. II: Estimation from the macroscopic current
Computational methods in Markov chains (60J22) Applications of continuous-time Markov processes on discrete state spaces (60J28) Biochemistry, molecular biology (92C40) Biomechanics (92C10)
Cites Work
- MCMC for hidden Markov models incorporating aggregation of states and filtering
- Stochastic processes in cell biology
- Computing characterizations of drugs for ion channels and receptors using Markov models
- Computational cell biology
- Markov chain Monte Carlo fitting of single-channel data from inositol trisphosphate receptors
- Generation of Finite Difference Formulas on Arbitrarily Spaced Grids
- On aggregated Markov processes
- Title not available (Why is that?)
- Title not available (Why is that?)
- Mathematical physiology. II: Systems physiology
Cited In (9)
- Computing characterizations of drugs for ion channels and receptors using Markov models
- Computing transient gating charge movement of voltage-dependent ion channels
- Coupled Markov chain model: Characterization of membrane channel currents with multiple conductance sublevels as partially coupled elementary pores
- Modelling non-Markovian fluctuations in intracellular biomolecular transport
- Fast-slow asymptotics for a Markov chain model of fast sodium current
- Computing optimal properties of drugs using mathematical models of single channel dynamics
- Markov models for ion channels: versatility versus identifiability and speed
- Title not available (Why is that?)
- Identifying the generator matrix of a stationary Markov chain using partially observable data
Uses Software
This page was built for publication: Computing rates of Markov models of voltage-gated ion channels by inverting partial differential equations governing the probability density functions of the conducting and non-conducting states
Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q288961)
