A division-dependent compartmental model with cyton and intracellular label dynamics

MaRDI QIDQ2913879zbMATH OpenFDO

Authors W. Clayton Thompson, H. Thomas Banks

Publication date 21 September 2012

Published in International Journal of Pure and Applied Mathematics (Search for Journal in Brave)

Full work available at URL http://www.ijpam.eu/contents/2012-77-1/12/index.html

zbMATH Keywords

cell division numbercell proliferationCFSEcyton modelsinverse problemslabel structured population dynamicspartial differential equations

Mathematics Subject Classification ID

PDEs in connection with biology, chemistry and other natural sciences (35Q92) Cell biology (92C37)

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• Quantifying CFSE label decay in flow cytometry data
• A general mathematical framework to model generation structure in a population of asynchronously dividing cells
• Estimating the division rate from indirect measurements of single cells
• A singular transport model describing cellular division
• A novel statistical analysis and interpretation of flow cytometry data
• Mathematical models of dividing cell populations: application to CFSE data
• Quantifying T lymphocyte turnover

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