A Markov-chain model for the analysis of high-resolution enzymatically ^18O-labeled mass spectra

DOI10.2202/1544-6115.1538MaRDI QIDQ2921179zbMATH OpenOpenAlexWikidataFDO

Authors Dirk Valkenborg, Tomasz Burzykowski

Publication date 7 October 2014

Published in Statistical Applications in Genetics and Molecular Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.2202/1544-6115.1538

zbMATH Keywords

Markov-chain modelquantitative proteomics\(^{18}\)O-labelinghigh-resolution mass spectrometrystable isotope labeling

Mathematics Subject Classification ID

General biostatistics (92B15)

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(3)

• A new protocol of analyzing isotope-coded affinity tag data from high-resolution LC-MS spec\-tro\-metry
• Variance function estimation in quantitative mass spectrometry with application to iTRAQ labeling
• A Markov-chain-based regression model with random effects for the analysis of \(^{18}\)O-labelled mass spectra

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