Evolution of viral life-cycle in response to cytotoxic T lymphocyte-mediated immunity

DOI10.1016/j.jtbi.2012.06.020zbMath1337.92130OpenAlexW2026575741WikidataQ48459790 ScholiaQ48459790MaRDI QIDQ292732

Yoram Louzoun, Vitaly V. Ganusov

Publication date: 9 June 2016

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2012.06.020

zbMATH Keywords

dynamicsevolutionimmunologyODEepitopes

Mathematics Subject Classification ID

Epidemiology (92D30) Medical epidemiology (92C60)

Uses Software

• DEDiscover

Cites Work

• Optimal viral production
• Evaluating the importance of within- and between-host selection pressures on the evolution of chronic pathogens
• HIV time hierarchy: winning the war while, loosing all the battles
• Optimizing within-host viral fitness: infected cell lifespan and virion production rate
• Optimal viral immune surveillance evasion strategies
• Trade-offs and the evolution of virulence of microparasites: do details matter?
• Evolution of virulence: interdependence, constraints, and selection using nested models

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